Model-Informed Precision Dosing of Tacrolimus: A Systematic Review of Population Pharmacokinetic Models and a Benchmark Study of Software Tools
Y Hoffert, N Dia, T Vanuytsel, R Vos, D Kuypers… - Clinical …, 2024 - Springer
Abstract Background and Objective Tacrolimus is an immunosuppressant commonly
administered after solid organ transplantation. It is characterized by a narrow therapeutic …
administered after solid organ transplantation. It is characterized by a narrow therapeutic …
Population pharmacokinetics study of tacrolimus in liver transplant recipients: a comparison between patients with or without liver cancer before surgery
H Bai, J Yun, Z Wang, Y Ma, W Liu - Frontiers in Pharmacology, 2024 - frontiersin.org
Background and Objective The main challenge for immunosuppressive therapy using
tacrolimus in liver transplantation is the considerable variability in its oral bioavailability and …
tacrolimus in liver transplantation is the considerable variability in its oral bioavailability and …
CYP3A4* 18B, CYP3A5* 3, and MDR1C3435T gene studies with tacrolimus pharmacokinetics in healthy Chinese subjects
YIN SHEN, Z Liu, J Zhang, X Xie, C Lin, H Song - 2024 - advance.sagepub.com
Aims: To investigate the effects of the CYP3A4* 18B, CYP3A5* 3, and MDR1C3435T gene
polymorphisms on the pharmacokinetics of tacrolimus in healthy Chinese subjects. Methods …
polymorphisms on the pharmacokinetics of tacrolimus in healthy Chinese subjects. Methods …