Immunopathology of chronic hepatitis B infection: role of innate and adaptive immune response in disease progression
A Khanam, JV Chua, S Kottilil - International Journal of Molecular …, 2021 - mdpi.com
More than 250 million people are living with chronic hepatitis B despite the availability of
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …
[HTML][HTML] Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure
EP Tsounis, E Tourkochristou, A Mouzaki… - World journal of …, 2021 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection, although preventable by vaccination, remains a global
health problem and a major cause of chronic liver disease. Although current treatment …
health problem and a major cause of chronic liver disease. Although current treatment …
An M0 macrophage-related prognostic model for hepatocellular carcinoma
Y Zhang, J Zou, R Chen - BMC cancer, 2022 - Springer
Background The role of M0 macrophages and their related genes in the prognosis of
hepatocellular carcinoma (HCC) remains poorly characterized. Methods Multidimensional …
hepatocellular carcinoma (HCC) remains poorly characterized. Methods Multidimensional …
Cholesterol accumulation on dendritic cells reverses chronic hepatitis B virus infection-induced dysfunction
H Zhao, Y Yu, Y Wang, L Zhao, A Yang, Y Hu… - Cellular & Molecular …, 2022 - nature.com
Chronic hepatitis B (CHB) infection remains a serious public health problem worldwide;
however, the relationship between cholesterol levels and CHB remains unclear. We isolated …
however, the relationship between cholesterol levels and CHB remains unclear. We isolated …
HBV vaccines: advances and development
F Mahmood, R Xu, MUN Awan, Y Song, Q Han, X Xia… - Vaccines, 2023 - mdpi.com
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …
N6-methyladenosine RNA methylation in liver diseases: from mechanism to treatment
L Yang, S Tian, X Zheng, M Zhang, X Zhou… - Journal of …, 2023 - Springer
Epigenetic modification occurring in RNA has become the hotspot of the field. N 6-
methyladenosine (m6A) methylation is the most abundant RNA internal modification mainly …
methyladenosine (m6A) methylation is the most abundant RNA internal modification mainly …
Deciphering the roles of myeloid derived suppressor cells in viral oncogenesis
A Glover, Z Zhang, C Shannon-Lowe - Frontiers in immunology, 2023 - frontiersin.org
Myeloid derived suppressor cells (MDSCs) are a heterogenous population of myeloid cells
derived from monocyte and granulocyte precursors. They are pathologically expanded in …
derived from monocyte and granulocyte precursors. They are pathologically expanded in …
[HTML][HTML] Innate and adaptive immune escape mechanisms of hepatitis B virus
HJ Zhao, YF Hu, QJ Han, J Zhang - World Journal of …, 2022 - ncbi.nlm.nih.gov
Chronic hepatitis B virus (HBV) infection is an international health problem with extremely
high mortality and morbidity rates. Although current clinical chronic hepatitis B (CHB) …
high mortality and morbidity rates. Although current clinical chronic hepatitis B (CHB) …
[HTML][HTML] Macrophage phenotypes and hepatitis B virus infection
Y Li, S Li, X Duan, C Yang, M Xu… - Journal of Clinical and …, 2020 - ncbi.nlm.nih.gov
Globally, hepatitis B virus (HBV) infection and its related liver diseases account for 780,000
deaths every year. Outcomes of HBV infection depend on the interaction between the virus …
deaths every year. Outcomes of HBV infection depend on the interaction between the virus …
A role for immune modulation in achieving functional cure for chronic hepatitis B among current changes in the landscape of new treatments
B Laupèze, V Vassilev, S Badur - Expert Review of …, 2023 - Taylor & Francis
ABSTRACT Introduction Chronic hepatitis B (CHB) is rarely cured using available
treatments. Barriers to cure are: 1) persistence of reservoirs of hepatitis B virus (HBV) …
treatments. Barriers to cure are: 1) persistence of reservoirs of hepatitis B virus (HBV) …