The challenge and promise of estimating the de novo mutation rate from whole‐genome comparisons among closely related individuals
Germline mutations are the raw material for natural selection, driving species evolution and
the generation of earth's biodiversity. Without this driver of genetic diversity, life on earth …
the generation of earth's biodiversity. Without this driver of genetic diversity, life on earth …
Genomic estimates of mutation and substitution rates contradict the evolutionary speed hypothesis of the latitudinal diversity gradient
The latitudinal diversity gradient (LDG) refers to a decrease in biodiversity from the equator
to the poles. The evolutionary speed hypothesis, backed by the metabolic theory of ecology …
to the poles. The evolutionary speed hypothesis, backed by the metabolic theory of ecology …
Linking temperature dependence of fitness effects of mutations to thermal niche adaptation
N Chen, QG Zhang - Journal of Evolutionary Biology, 2023 - academic.oup.com
Fitness effects of mutations may generally depend on temperature that influences all rate‐
limiting biophysical and biochemical processes. Earlier studies suggested that high …
limiting biophysical and biochemical processes. Earlier studies suggested that high …
Thermal stress and mutation accumulation increase heat shock protein expression in Daphnia
Understanding the short-and long-term consequences of climate change is a major
challenge in biology. For aquatic organisms, temperature changes and drought can lead to …
challenge in biology. For aquatic organisms, temperature changes and drought can lead to …
Does geographic variation in thermal tolerance in Daphnia represent trade-offs or conditional neutrality?
BL Coggins, AC Pearson, LY Yampolsky - Journal of Thermal Biology, 2021 - Elsevier
Geographic variation in thermal tolerance in Daphnia seems to represent genetic load at the
loci specifically responsible for heat tolerance resulting from conditional neutrality. We see …
loci specifically responsible for heat tolerance resulting from conditional neutrality. We see …
Consequences of mutation accumulation for growth performance are more likely to be resource-dependent at higher temperatures
XL Chu, QG Zhang - BMC Ecology and Evolution, 2021 - Springer
Background Mutation accumulation (MA) has profound ecological and evolutionary
consequences. One example is that accumulation of conditionally neutral mutations leads to …
consequences. One example is that accumulation of conditionally neutral mutations leads to …