[HTML][HTML] The complexity of nicotinamide adenine dinucleotide (NAD), hypoxic, and aryl hydrocarbon receptor cell signaling in chronic kidney disease

CS Curran, JB Kopp - Journal of Translational Medicine, 2023 - Springer
Early-stage detection of chronic kidney diseases (CKD) is important to treatment that may
slow and occasionally halt CKD progression. CKD of diverse etiologies share similar …

[HTML][HTML] Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases

LA Bravo-Vázquez, S Paul, MG Colín-Jurado… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …

[HTML][HTML] Epigenetic regulation in adult neural stem cells

J Shi, Z Wang, Z Wang, G Shao, X Li - Frontiers in Cell and …, 2024 - frontiersin.org
Neural stem cells (NSCs) exhibit self-renewing and multipotential properties. Adult NSCs
are located in two neurogenic regions of adult brain: the ventricular-subventricular zone (V …

Extracellular vesicles: illuminating renal pathophysiology and therapeutic frontiers

L Shi, H Zeng, Z An, W Chen, Y Shan, C Ji… - European Journal of …, 2024 - Elsevier
Extracellular vesicles (EVs) are minute sacs released by cells into the extracellular milieu,
harboring an array of biomolecules including proteins, nucleic acids, and lipids. Notably, a …

Small extracellular vesicles–A host for advanced bioengineering and “Trojan Horse” of non-coding RNAs

A Bryja, Ł Zadka, M Farzaneh, M Zehtabi… - Life Sciences, 2023 - Elsevier
Small extracellular vesicles (sEVs) as a type of membranous vesicle that can be released by
cells into the extracellular space. The relationship between sEVs and non-coding RNAs …

[HTML][HTML] Exosomes in the pathogenesis and treatment of cancer-related cachexia

Q Ru, L Chen, G Xu, Y Wu - Journal of Translational Medicine, 2024 - Springer
Cancer-related cachexia is a metabolic syndrome characterized by weight loss, adipose
tissue decomposition, and progressive skeletal muscle atrophy. It is a major complication of …

Mitochondrial iron regulation as an emerging target in ischemia/reperfusion injury during kidney transplantation

Y Qi, M Hu, Z Wang, W Shang - Biochemical Pharmacology, 2023 - Elsevier
The injury caused by ischemia and subsequent reperfusion (I/R) is inevitable during kidney
transplantation and its current management remains unsatisfactory. Iron is considered to …

[HTML][HTML] Small RNA sequencing reveals snoRNAs and piRNA-019825 as novel players in diabetic kidney disease

LM 't Hart, JA de Klerk, GA Bouland, JHD Peerlings… - Endocrine, 2024 - Springer
Introduction Micro-and macrovascular complications are common among persons with type
2 diabetes. Recently there has been growing interest to investigate the potential of …

Circulating small non-coding RNAs associate with kidney function in people with type 2 diabetes

LM 't Hart, GA Bouland, JA de Klerk, MT Blom… - medRxiv, 2022 - medrxiv.org
Aims/hypothesis Micro-and macrovascular complications are common among persons with
type 2 diabetes. Interest into the potential of circulating small non-coding RNAs (sRNAs) as …