Drug resistance and tolerance in fungi
J Berman, DJ Krysan - Nature Reviews Microbiology, 2020 - nature.com
Systemic fungal infections pose a serious clinical problem. Treatment options are limited,
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …
Critical review on biofilm methods
Biofilms are widespread in nature and constitute an important strategy implemented by
microorganisms to survive in sometimes harsh environmental conditions. They can be …
microorganisms to survive in sometimes harsh environmental conditions. They can be …
Development and regulation of single- and multi-species Candida albicans biofilms
MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …
[HTML][HTML] Antifungal therapy: new advances in the understanding and treatment of mycosis
L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
Candida albicans biofilm growth and dispersal: contributions to pathogenesis
G Wall, D Montelongo-Jauregui, BV Bonifacio… - Current opinion in …, 2019 - Elsevier
Highlights•Biofilm formation is a major contributor to pathogenesis during Candida
infection.•C. albicans biofilm formation is a multi-step, highly regulated process.•Cells in …
infection.•C. albicans biofilm formation is a multi-step, highly regulated process.•Cells in …
[HTML][HTML] Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable
attention as a source of healthcare–associated infections. We report that this highly virulent …
attention as a source of healthcare–associated infections. We report that this highly virulent …
[HTML][HTML] An update on Candida tropicalis based on basic and clinical approaches
DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …
widely considered the second most virulent Candida species, only preceded by C. albicans …
Candida albicans biofilm–induced vesicles confer drug resistance through matrix biogenesis
R Zarnowski, H Sanchez, AS Covelli, E Dominguez… - PLoS …, 2018 - journals.plos.org
Cells from all kingdoms of life produce extracellular vesicles (EVs). Their cargo is protected
from the environment by the surrounding lipid bilayer. EVs from many organisms have been …
from the environment by the surrounding lipid bilayer. EVs from many organisms have been …
Inhibition of Bacterial Adhesion and Antibiofilm Activities of a Glycolipid Biosurfactant from Lactobacillus rhamnosus with Its Physicochemical and Functional …
M Patel, AJ Siddiqui, WS Hamadou, M Surti… - Antibiotics, 2021 - mdpi.com
Biosurfactants derived from different microbes are an alternative to chemical surfactants,
which have broad applications in food, oil, biodegradation, cosmetic, agriculture, pesticide …
which have broad applications in food, oil, biodegradation, cosmetic, agriculture, pesticide …
Fungal biofilm resistance
G Ramage, R Rajendran, L Sherry… - International journal of …, 2012 - Wiley Online Library
Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …
problem. One of the major reasons behind this is the impact that these have upon treatment …