The tumor microenvironment and the estrogen loop in thyroid cancer

N Denaro, R Romanò, S Alfieri, A Dolci, L Licitra… - Cancers, 2023 - mdpi.com
Simple Summary The composite network of stromal, immune, vascular and cancer cells,
which constitutes the tumor microenvironment (TME), has emerged as a player in thyroid …

Multi-omics and management of follicular carcinoma of the thyroid

TE Luvhengo, I Bombil, A Mokhtari, MS Moeng… - Biomedicines, 2023 - mdpi.com
Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid gland,
accounting for up to 20% of all primary malignant tumors in iodine-replete areas. The …

Association between eight autoimmune diseases and thyroid cancer: a Nationwide Cohort Study

SK Park, JH Ryoo, MH Kim, JY Jung, YS Jung, KN Kim… - Thyroid, 2024 - liebertpub.com
Background: It has often been reported that thyroid-specific autoimmune diseases (ADs),
such as Hashimoto's thyroiditis and Graves' disease, could increase the risk of thyroid …

Tumor-associated tertiary lymphoid structures in cancer: implications for immunotherapy

M Langouo Fontsa, F Padonou… - Expert Review of …, 2024 - Taylor & Francis
Introduction Tertiary lymphoid structures (TLS) arise at chronic inflammatory sites where they
function as miniature lymph nodes to generate immune responses, which can be beneficial …

The relationship between thyroid peroxidase antibody and differentiated thyroid cancer: a systematic review and meta-analysis

H Zhang, L Tian, X Wang, X Shi - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Thyroglobulin antibody (TgAb) has been found to be associated with the
occurrence and development of differentiated thyroid cancer (DTC) for several years, but …

Elastographic Evaluation of Thyroid Nodules in Children and Adolescents with Hashimoto's Thyroiditis and Nodular Goiter with Reference to Cytological and/or …

H Borysewicz-Sańczyk, B Sawicka… - Journal of Clinical …, 2022 - mdpi.com
There are data indicating the coexistence of papillary thyroid carcinoma and autoimmune
thyroiditis (AIT) in children. The aim of the study was elastographic evaluation of thyroid …

Selective anti-CXCR2 receptor blockade by AZD5069 inhibits CXCL8-mediated pro-tumorigenic activity in human thyroid cancer cells in vitro

F Coperchini, A Greco, E Petrosino, L Croce… - Journal of …, 2024 - Springer
Background Thyroid cancer is the most common endocrine malignancy. Current therapies
are successful, however some patients progress to therapeutically refractive disease. The …

Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment

M Borowczyk, M Kaczmarek-Ryś… - Journal of …, 2024 - Springer
Purpose Differentiated thyroid cancer (DTC) presents a complex clinical challenge,
especially in patients with distant metastases and resistance to standard treatments. This …

FDG uptake reflects an immune‐enriched subtype of thyroid cancer: Clinical implications of imaging‐based molecular characterization

HY Suh, H Choi, SW Cho, JC Paeng… - Cancer …, 2023 - Wiley Online Library
Introduction Iodine and FDG uptakes have been established as methods to define the
biological properties of thyroid cancer. As various cells in the tumor microenvironment (TME) …

Can we yet use tertiary lymphoid structures as predictive biomarkers for immunotherapy response in melanoma?

F Padonou, T Vanhulst… - Current Opinion in …, 2024 - journals.lww.com
Can we yet use tertiary lymphoid structures as predictive biomarkers for immunotherapy
response in melanoma? Page 1 CURRENT OPINION Can we yet use tertiary lymphoid structures …