Reproductive diseases are a long‐standing problem and have become more common in the
world. Currently, 15% of the world's population suffers from infertility, and half of them are …

Abstract Poly (A)-tail-mediated post-transcriptional regulation of maternal mRNAs is vital in
the oocyte-to-embryo transition (OET). Nothing is known about poly (A) tail dynamics during …

After fertilization, sperm and oocyte fused and gave rise to a zygote which is the beginning of
a new life. Then the embryonic development is monitored and regulated precisely from the …

Oocyte maturation is vital to attain full competence required for fertilization and
embryogenesis. NLRP14 is preferentially expressed in mammalian oocytes and early …

The subcortical maternal complex (SCMC), composed of several maternal‐effect genes, is
vital for the development of oocytes and early embryos. Variants of SCMC‐encoding genes …

Oocyte maturation arrest, fertilization failure, and early embryonic arrest are important
causes of female infertility, whereas the genetic events that contribute to these processes …

Phosphorylation is a key post-translational modification regulating protein function and
biological outcomes. However, the phosphorylation dynamics orchestrating mammalian …

Purpose Oocyte maturation defect (OOMD) is a rare cause of in vitro fertilization failure
characterized by the production of immature oocytes. Compound heterozygous or …

STUDY QUESTION What is the genetic basis of female infertility involving abnormal oocyte
morphology with the production of a large first polar body (PB1)? SUMMARY ANSWER The …

Preimplantation embryonic arrest is an important pathogenesis of female infertility, but little
is known about the genetic factors behind this phenotype. MEI4 is an essential protein for …