Clinical neurology and epidemiology of the major neurodegenerative diseases
MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
Primary progressive aphasia: a clinical approach
The primary progressive aphasias are a heterogeneous group of focal 'language-
led'dementias that pose substantial challenges for diagnosis and management. Here we …
led'dementias that pose substantial challenges for diagnosis and management. Here we …
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference
The heterogeneity of neurodegenerative diseases is a key confound to disease
understanding and treatment development, as study cohorts typically include multiple …
understanding and treatment development, as study cohorts typically include multiple …
Typical and atypical pathology in primary progressive aphasia variants
EG Spinelli, ML Mandelli, ZA Miller… - Annals of …, 2017 - Wiley Online Library
Objective To characterize in vivo signatures of pathological diagnosis in a large cohort of
patients with primary progressive aphasia (PPA) variants defined by current diagnostic …
patients with primary progressive aphasia (PPA) variants defined by current diagnostic …
The role of noradrenaline in cognition and cognitive disorders
Many aspects of cognition and behaviour are regulated by noradrenergic projections to the
forebrain originating from the locus coeruleus, acting through alpha and beta …
forebrain originating from the locus coeruleus, acting through alpha and beta …
Clinicopathological correlations in behavioural variant frontotemporal dementia
Accurately predicting the underlying neuropathological diagnosis in patients with
behavioural variant frontotemporal dementia (bvFTD) poses a daunting challenge for …
behavioural variant frontotemporal dementia (bvFTD) poses a daunting challenge for …
Frontotemporal dementia, where do we stand? A narrative review
A Antonioni, EM Raho, P Lopriore, AP Pace… - International journal of …, 2023 - mdpi.com
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
Prevalence of amyloid‐β pathology in distinct variants of primary progressive aphasia
D Bergeron, ML Gorno‐Tempini… - Annals of …, 2018 - Wiley Online Library
Objective To estimate the prevalence of amyloid positivity, defined by positron emission
tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological …
tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological …
Frontotemporal dementia: latest evidence and clinical implications
JJ Young, M Lavakumar, D Tampi… - Therapeutic …, 2018 - journals.sagepub.com
Background: Frontotemporal dementia (FTD) describes a cluster of neurocognitive
syndromes that present with impairment of executive functioning, changes in behavior, and …
syndromes that present with impairment of executive functioning, changes in behavior, and …