Epigenetics in hepatocellular carcinoma

GP Nagaraju, B Dariya, P Kasa, S Peela… - Seminars in cancer …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and
has a high fatality rate. Genetic and epigenetic aberrations are commonly observed in HCC …

The roles of epigenetic regulation and the tumor microenvironment in the mechanism of resistance to systemic therapy in hepatocellular carcinoma

K Oura, A Morishita, S Hamaya, K Fujita… - International Journal of …, 2023 - mdpi.com
Primary liver cancer is the sixth most common cancer and the third most common cause of
cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is a major histologic type …

The emerging influences of alpha-fetoprotein in the tumorigenesis and progression of hepatocellular carcinoma

Y Xu, Q Guo, L Wei - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma is characterized by aggressive invasion, rapid
progress and poor prognosis. Since hepatocellular carcinoma is a highly heterogeneous …

The pathogenesis of liver cancer and the therapeutic potential of bioactive substances

S Gao, X Jiang, L Wang, S Jiang, H Luo… - Frontiers in …, 2022 - frontiersin.org
Liver cancer is the third most common cause of cancer-related deaths in the world and has
become an urgent problem for global public health. Bioactive substances are widely used …

The association between alcohol consumption and the risk of hepatocellular carcinoma according to glycemic status in Korea: A nationwide population-based study

EJ Cho, GE Chung, JJ Yoo, Y Cho, DW Shin… - PLoS …, 2023 - journals.plos.org
Background Alcohol and diabetes are known risk factors for hepatocellular carcinoma
(HCC); however, it is unclear whether the association between alcohol consumption and …

Association of diabetes mellitus and alcohol abuse with cancer: Molecular mechanisms and clinical significance

BQ Lam, R Srivastava, J Morvant, S Shankar… - Cells, 2021 - mdpi.com
Diabetes mellitus (DM), one of the metabolic diseases which is characterized by sustained
hyperglycemia, is a life-threatening disease. The global prevalence of DM is on the rise …

Association between pro-inflammatory diet and liver cancer risk: A Systematic Review and Meta-Analysis

K Chen, F Yang, X Zhu, G Qiao, C Zhang, J Tao… - Public Health …, 2023 - cambridge.org
Objective: This systematic review aimed to investigate the association between dietary
inflammatory potential and liver cancer to provide evidence regarding scientific dietary …

原发性肝癌的流行病学及其危险因素研究进展

陈倩倩, 芮法娟, 倪文婧, 李婕 - 中国全科医学, 2024 - chinagp.net
原发性肝癌是世界上常见的恶性肿瘤之一, 具有较高的发病率和死亡率. 本文详述了目前我国原
发性肝癌的流行病学情况, 人群归因分值及其相关危险因素. 本文通过检索PubMed, Web of …

[HTML][HTML] The effects of moderate alcohol consumption on non-alcoholic fatty liver disease

H Oh, W Sohn, YK Cho - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is accepted as a counterpart to alcohol-related
liver disease because it is defined as hepatic steatosis without excessive use of alcohol …

GARS is implicated in poor survival and immune infiltration of hepatocellular carcinoma

J Wang, B Yang, D Wang, R Han, Z Bi, L Lin - Cellular Signalling, 2022 - Elsevier
Objective Hepatocellular carcinoma (HCC) is a malignant cancer with poor survival rates.
Glycyl-tRNA synthetase (GARS) is a tRNA-charging enzyme that can serve as a biomarker …