Until recently, understanding the regulatory behavior of cells has been pursued through
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …

Discovering the gene expression signature associated with a cellular state is one of the
basic quests in majority of biological studies. For most of the clinical and cellular …

Integrated-omics approaches are quickly spreading across microbiology research labs,
leading to (i) the possibility of detecting previously hidden features of microbial cells like …

Since the main ultimate goal of farm animal raising is the production of proteins for human
consumption, research tools to investigate proteins play a major role in farm animal and …

The quest for the ideal therapeutic target in chronic kidney disease (CKD) has been riddled
with many obstacles stemming from the molecular complexity of the disease and its co …

Wheat plants are very sensitive to high temperature stress during grain filling. Effects of heat
priming applied to the first generation on tolerance of the successive generation to post …

Highlights•The reductionist drug discovery approach entails high attrition rates.•Topology-
based pathway analysis can unravel the disease mechanism (s).•Candidate targets can be …

Background Pollen of common ragweed (Ambrosia artemisiifolia) is a main cause of allergic
diseases in Northern America. The weed has recently become spreading as a neophyte in …

Mesenchymal stem cells (MSCs) are gaining increasing prominence as an effective
regenerative cellular therapy. However, ensuring consistent and reliable effects across …

Kidney diseases manifest in progressive loss of renal function, which ultimately leads to
complete kidney failure. The mechanisms underlying the origins and progression of kidney …