Despite significant improvements in reperfusion strategies, acute coronary syndromes all too
often culminate in a myocardial infarction (MI). The consequent MI can, in turn, lead to …

Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can
identify pathogen-associated molecular patterns (PAMPs) and damage-associated …

Background: Ferroptosis has been found to play an important role in myocardial ischemia
reperfusion (MIR) injury (MIRI). This study aimed to explore whether the improvement effect …

Introduction Targeted protein degradation represents a promising therapeutic approach,
while diabetic cardiomyopathy (DCM) arises as a consequence of aberrant insulin secretion …

Background Exosomes carrying micro ribonucleic acids (miRNAs) protect against
myocardial ischemic injury. In the study, we sought to investigate the protective effect …

Toll-like receptor 3 (TLR3) is an important member of the innate immune response receptor
toll-like receptors (TLRs) family, which plays a vital role in regulating immune response …

Ischemic cardiomyopathy leads to inflammation and left ventricular (LV) dysfunction. Animal
studies provided evidence for cardioprotective effects of the endocannabinoid system …

Myocardial infarction (MI) is a life-threatening condition among patients with cardiovascular
diseases. MI increases the risk of stroke and heart failure and is a leading cause of morbidity …

Background: Ischaemia-reperfusion injury (IRI) is the damage that occurs when blood flow is
restored to a tissue or organ after a period of ischaemia. Postconditioning is a therapeutic …

Cardiac fibrosis, associated with right heart dysfunction, results in significant morbidity and
mortality. Stimulated by various cellular and humoral stimuli, cardiac fibroblasts …