Celecoxib in cancer therapy and prevention–review

N Tołoczko-Iwaniuk… - Current Drug …, 2019 - ingentaconnect.com
Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …

[HTML][HTML] Molecular signaling in tumorigenesis of gastric cancer

F Molaei, MM Forghanifard, Y Fahim… - Iranian biomedical …, 2018 - ncbi.nlm.nih.gov
Gastric cancer (GC) is regarded as the fifth most common cancer and the third cause of
cancer-related deaths worldwide. Mechanism of GC pathogenesis is still unclear and relies …

LncRNA SNHG15 regulates EGFR-TKI acquired resistance in lung adenocarcinoma through sponging miR-451 to upregulate MDR-1

J Huang, B Pan, G Xia, J Zhu, C Li, J Feng - Cell death & disease, 2020 - nature.com
Lung adenocarcinoma (LUAD) is the main component of non-small-cell lung cancer
(NSCLC) and causes a great health concern globally. The top priority of LUAD treatment is …

miR-23b-3p and miR-130a-5p affect cell growth, migration and invasion by targeting CB1R via the Wnt/β-catenin signaling pathway in gastric carcinoma

X Xian, L Tang, C Wu, L Huang - OncoTargets and therapy, 2018 - Taylor & Francis
Background Gastric cancer (GC) is the most common malignancy and third leading cause of
cancer mortality worldwide. The identification of a sensitive biomarker as well as effective …

A comprehensive evaluation of clinical efficacy and safety of celecoxib in combination with chemotherapy in metastatic or postoperative recurrent gastric cancer …

Q Guo, Q Li, J Wang, M Liu, Y Wang, Z Chen, Y Ye… - Medicine, 2019 - journals.lww.com
Aim: To evaluate the efficacy and safety of celecoxib combined with chemotherapy in the
treatment of metastatic or postoperative recurrent gastric cancer. Methods: This preliminary …

The four horsemen in colon cancer

MA Hernández-Luna, S Lopez-Briones… - Journal of …, 2019 - Wiley Online Library
Worldwide, neoplasms of the gastrointestinal tract have a very high incidence and mortality.
Among these, colorectal cancer, which includes colon and rectum malignancies …

[HTML][HTML] Role of p53 methylation in manganese-induced cyclooxygenase-2 expression in BV2 microglial cells

X Liu, C Yao, Y Tang, X Liu, C Duan, C Wang… - Ecotoxicology and …, 2022 - Elsevier
Manganese (Mn) is an essential cofactor for many enzymes and plays an important role in
normal growth and development. However, excess exposure to manganese (Mn) may be an …

Pathological and pharmacological functions of the metabolites of polyunsaturated fatty acids mediated by cyclooxygenases, lipoxygenases, and cytochrome P450s in …

YW Meng, JY Liu - Pharmacology & Therapeutics, 2024 - Elsevier
Oxylipins have garnered increasing attention because they were consistently shown to play
pathological and/or pharmacological roles in the development of multiple cancers. Oxylipins …

[HTML][HTML] Gliquidone alleviates diabetic nephropathy by inhibiting notch/snail signaling pathway

H Tian, J Yang, Z Xie, J Liu - Cellular Physiology and Biochemistry, 2018 - karger.com
Background/Aims: Diabetic nephropathy is a common complication of diabetes. This study
explored the renal protective effect and possible mechanism of gliquidone in mice with …

Notch signaling pathway in cancer: from mechanistic insights to targeted therapies

Q Shi, C Xue, Y Zeng, X Yuan, Q Chu, S Jiang… - … and Targeted Therapy, 2024 - nature.com
Notch signaling, renowned for its role in regulating cell fate, organ development, and tissue
homeostasis across metazoans, is highly conserved throughout evolution. The Notch …