Mineral bone disease (MBD) is a common complication of chronic kidney disease (CKD)
characterized by disruption of normal mineral homeostasis within the body. One or more of …

Bone and mineral metabolism becomes dysregulated with progression of chronic kidney
disease (CKD), and increasing levels of parathyroid hormone serve as an adaptive …

Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range”
are highly associated with increased cardiovascular disease risk and mortality in the general …

Many of the> 2 million animal species that inhabit Earth have developed survival
mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration …

Background Treating hyperphosphatemia is a tenet of dialysis care. This trial assessed the
safety and efficacy of tenapanor for the management of hyperphosphatemia. Methods In this …

Chronic kidney disease is a devastating condition resulting from irreversible loss of nephron
numbers and function and leading to end-stage renal disease and mineral disorders …

Background Tumor lysis syndrome (TLS) is the most common life-threatening oncological
emergency encountered by physicians treating children with lymphoproliferative …

Chronic kidney disease (CKD) affects more than 10% of the world population and leads to
excess morbidity and mortality (with cardiovascular disease as a leading cause of death) …

States of hypo‐and hyperphosphatemia have deleterious consequences including
rickets/osteomalacia and renal/cardiovascular disease, respectively. Therefore, the …

Importance Guidelines restricting use of calcium-based phosphate binders in all patients
with end-stage renal disease owing to their potential contribution to increased …