Insights into the molecular targets and emerging pharmacotherapeutic interventions for nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease
worldwide. With no Food and Drug Administration approved drugs, current treatment options …
worldwide. With no Food and Drug Administration approved drugs, current treatment options …
[HTML][HTML] Fructose and NAFLD: the multifaceted aspects of fructose metabolism
P Jegatheesan, JP De Bandt - Nutrients, 2017 - mdpi.com
Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …
Isocaloric diets high in animal or plant protein reduce liver fat and inflammation in individuals with type 2 diabetes
M Markova, O Pivovarova, S Hornemann, S Sucher… - Gastroenterology, 2017 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is associated with increased
risk of hepatic, cardiovascular, and metabolic diseases. High-protein diets, rich in …
risk of hepatic, cardiovascular, and metabolic diseases. High-protein diets, rich in …
[HTML][HTML] Pemafibrate, a new selective PPARα modulator: drug concept and its clinical applications for dyslipidemia and metabolic diseases
S Yamashita, D Masuda, Y Matsuzawa - Current atherosclerosis reports, 2020 - Springer
Abstract Purpose of Review Reduction of serum low-density lipoprotein cholesterol (LDL-C)
levels by statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) …
levels by statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) …
[HTML][HTML] Epidemiology and pathophysiology of the association between NAFLD and metabolically healthy or metabolically unhealthy obesity
The prevalence of nonalcoholic fatty liver disease (NAFLD) is continuing to rise in many
countries, paralleling the epidemic of obesity worldwide. In the last years, the concept of …
countries, paralleling the epidemic of obesity worldwide. In the last years, the concept of …
Fibroblast growth factor 21 in non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of pathologies ranging
from uncomplicated hepatic fat accumulation to a state of lobular inflammation and …
from uncomplicated hepatic fat accumulation to a state of lobular inflammation and …
New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
Potential mechanisms underlying the ameliorative effect of Lactobacillus paracasei FZU103 on the lipid metabolism in hyperlipidemic mice fed a high-fat diet
XC Lv, M Chen, ZR Huang, WL Guo, LZ Ai… - Food Research …, 2021 - Elsevier
Lactobacillus paracasei FZU103, a probiotic previously isolated from the traditional brewing
process of Hongqu rice wine, may have the beneficial effect of improving the disorder of lipid …
process of Hongqu rice wine, may have the beneficial effect of improving the disorder of lipid …
[HTML][HTML] Update on dyslipidemia in hypothyroidism: the mechanism of dyslipidemia in hypothyroidism
H Liu, D Peng - Endocrine Connections, 2022 - ec.bioscientifica.com
Hypothyroidism is often associated with elevated serum levels of total cholesterol, LDL-C
and triglycerides. Thyroid hormone (TH) affects the production, clearance and transformation …
and triglycerides. Thyroid hormone (TH) affects the production, clearance and transformation …
Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity
MR Taskinen, S Söderlund, LH Bogl… - Journal of internal …, 2017 - Wiley Online Library
Background Overconsumption of dietary sugars, fructose in particular, is linked to
cardiovascular risk factors such as type 2 diabetes, obesity, dyslipidemia and nonalcoholic …
cardiovascular risk factors such as type 2 diabetes, obesity, dyslipidemia and nonalcoholic …