Importance Medication treatment for opioid use disorder (MOUD) is efficacious, but
comorbid stimulant use and other behavioral health problems often undermine efficacy …

Drug addiction, one of the major health problems worldwide, is characterized by the loss of
control in drug intake, craving, and withdrawal. At the individual level, drugs of abuse …

The United States is in an era of unprecedented levels of drug-related mortality, evidenced
by an exponential increase in deaths over a recent 38-year period. 1 The recent drivers of …

The current overdose and broader public health crisis involving illicit drug use is often
referred to as the “opioid” or “fentanyl” crisis. Clearly there is extensive data on the profound …

Abstract Cocaine Use Disorder (CUD) is a significant public health problem associated with
elevated morbidity and mortality within the United States. Current behavioral treatments …

Cocaine use disorder (CUD) is a devastating disorder, impacting both individuals and
society. Individuals with CUD face many barriers in accessing treatment for CUD, and most …

Atypical dopamine transporter (DAT) inhibitors have shown therapeutic potential in the
preclinical models of psychostimulant use disorders (PSUD). In rats, 1-(4-(2-((bis (4 …

Abstract The United States is currently in the fourth wave of the overdose crisis wherein
stimulants together with fentanyl are the major drivers of overdose deaths. To date, there has …

Background This study tested an adaptive intervention for optimizing abstinence outcomes
over phases of treatment for cocaine use disorder using a SMART design. Phase 1 …

Substance use disorders (SUDs) constitute a growing global health crisis, yet many
limitations and challenges exist in SUD treatment research, including the lack of objective …