Systematic review and meta-analysis of vancomycin-induced nephrotoxicity associated with dosing schedules that maintain troughs between 15 and 20 milligrams per …

SJ van Hal, DL Paterson, TP Lodise - Antimicrobial agents and …, 2013 - Am Soc Microbiol
In an effort to maximize outcomes, recent expert guidelines recommend more-intensive
vancomycin dosing schedules to maintain vancomycin troughs between 15 and 20 mg/liter …

MRGPRX2 and adverse drug reactions

BD McNeil - Frontiers in immunology, 2021 - frontiersin.org
Many adverse reactions to therapeutic drugs appear to be allergic in nature, and are thought
to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug …

[HTML][HTML] Innovative approaches to optimizing the delivery of vancomycin in individual patients

MP Pai, M Neely, KA Rodvold, TP Lodise - Advanced drug delivery reviews, 2014 - Elsevier
The delivery of personalized antimicrobial therapy is a critical component in the treatment of
patients with invasive infections. Vancomycin, the drug of choice for infections due to …

Chitosan‐based hydrogels for infected wound treatment

X Wang, R Song, M Johnson, P Shen… - Macromolecular …, 2023 - Wiley Online Library
Wound infections slow down the healing process and lead to complications such as
septicemia, osteomyelitis, and even death. Although traditional methods relying on …

Vancomycin-induced thrombocytopenia: a narrative review

M Mohammadi, Z Jahangard-Rafsanjani, A Sarayani… - Drug safety, 2017 - Springer
Thrombocytopenia has been reported as an adverse reaction of numerous drugs.
Vancomycin is often overlooked as a culprit but has been associated with several cases of …

Design, synthesis and antibacterial activity of chalcones against MSSA and MRSA planktonic cells and biofilms

MAR Garcia, RS Theodoro, JCO Sardi, MB Santos… - Bioorganic …, 2021 - Elsevier
Staphylococcus aureus is the one of the most successful modern pathogens. The same
bacterium that lives as a skin and mucosal commensal can be transmitted in health-care and …

In vitro synergy of 5-nitrofurans, vancomycin and sodium deoxycholate against Gram-negative pathogens

C Olivera, VVH Le, C Davenport… - Journal of medical …, 2021 - microbiologyresearch.org
Introduction. There is an urgent need for effective therapies against bacterial infections,
especially those caused by antibiotic-resistant Gram-negative pathogens. Hypothesis …

Therapeutic drug-induced platelet apoptosis: an overlooked issue in pharmacotoxicology

RM Thushara, M Hemshekhar, K Kemparaju… - Archives of …, 2014 - Springer
The surfacing of the applied fields of biology such as, biotechnology, pharmacology and
drug discovery was a boon to the modern man. However, it had its share of disadvantages …

[HTML][HTML] Steady-state pharmacokinetics of vancomycin in children admitted to pediatric intensive care unit of a tertiary referral center

NB Mali, MS Tullu, PP Wandalkar… - Indian Journal of …, 2019 - ncbi.nlm.nih.gov
Aims and objectives Vancomycin is a drug of choice for various gram-positive bacterial
(GPB) infections and is largely prescribed to pediatric intensive care unit (PICU) patients …

A 10‐year retrospective study of antibacterial‐induced thrombocytopenia in a women and children hospital using China Hospital Pharmacovigilance System and …

J Yang, C Cai, X Pan, W Chen… - British Journal of …, 2024 - Wiley Online Library
Aims We aimed to investigate antibacterial‐induced thrombocytopenia using the China
Hospital Pharmacovigilance System (CHPS) in conjunction with Visual Basic for …