Covering: up to 2022 Pentacyclic triterpenoids are important natural bioactive substances
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …

Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …

Obesity is a major health risk still lacking effective pharmacological treatment. A potent anti-
obesity agent, celastrol, has been identified in the roots of Tripterygium wilfordii. However …

This systematic review identified various bioactive compounds which have the potential to
serve as novel drugs or leads against acute myeloid leukemia. Acute myeloid leukemia …

Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of
Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic …

Covering: 2011–2022 The low amounts of terpenoids produced in plants and the difficulty in
synthesizing these complex structures have stimulated the production of terpenoid …

Metabolic diseases are becoming increasingly common in modern society. Therefore, it is
essential to develop effective drugs or new treatments for metabolic diseases. As an active …

Miltiradiene is a key intermediate in the biosynthesis of many important natural diterpene
compounds with significant pharmacological activity, including triptolide, tanshinones …

Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes
ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM) …

Celastrol, a quinonemethide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …