Two highly prevalent diseases, Type-2 diabetes mellitus and coronary heart disease (CHD),
share risk factors. Excess levels of LDL-cholesterol have been overemphasized to uniformly …

Whether or not Lp (a) plasma levels are affected by the apoB R3500Q mutation, which
causes Familial Defective apoB (FDB), is still a matter of debate. We have analyzed 300 …

Two enhancer regions upstream of the apolipoprotein (a)(apo (a)) gene were amplified and
sequenced from subjects who were known to express abnormally high or low amounts of …

Background: The association between lipoprotein (a) levels, apolipoprotein (a) size and the
(TTTTA) n polymorphism which is located in the 5′ non-coding region of the apo (a) gene …

Apolipoprotein [a](apo [a]) gene size is a major predictor of lipoprotein [a] level. To
determine genetic predictors of allele-specific apo [a] levels beyond gene size, we evaluated …

Background Evidence has been provided that lipoprotein (a)(Lp (a)) may be an important
cardiovascular risk factor. Recognition of potential Lp (a) variability associated with common …

Abstract Apolipoprotein [a](apo [a]), a unique component of atherogeniclipoprotein [a], is
highly polymorphic in human and nonhuman primates. Nullalleles, producing no detectable …

US6225451B1 - Chromosome 11-linked coronary heart disease susceptibility gene CHD1 -
Google Patents US6225451B1 - Chromosome 11-linked coronary heart disease susceptibility …

A high plasma concentration of lipoprotein (a)[Lp (a)] confers an increased risk for the
development of coronary heart disease. Hormones, such as oestrogen, are some of the few …

The apo (a)[apolipoprotein (a)] gene is responsible for variations in plasma lipoprotein (a),
high levels of which are a risk factor for atherosclerosis and myocardial infarction. The apo …