[HTML][HTML] Revolutionizing cancer immunotherapy: unleashing the potential of bispecific antibodies for targeted treatment

X Guo, Y Wu, Y Xue, N Xie, G Shen - Frontiers in Immunology, 2023 - frontiersin.org
Recent progressions in immunotherapy have transformed cancer treatment, providing a
promising strategy that activates the immune system of the patient to find and eliminate …

[HTML][HTML] Introduction of Carbonyl Groups into Antibodies

EL Gulyak, VA Alferova, VA Korshun, KA Sapozhnikova - Molecules, 2023 - mdpi.com
Antibodies and their derivatives (scFv, Fabs, etc.) represent a unique class of biomolecules
that combine selectivity with the ability to target drug delivery. Currently, one of the most …

A mini review on recent progress of microfluidic systems for antibody development

K Omidfar, S Kashanian - Journal of Diabetes & Metabolic Disorders, 2024 - Springer
Objectives Antibody is specific reagent that be utilized in various field of biomedical
research. Monoclonal antibodies are mostly produced using two common techniques …

A SARS-CoV-2 Interaction Dataset and VHH Sequence Corpus for Antibody Language Models

H Tsuruta, H Yamazaki, R Maeda, R Tamura… - arXiv preprint arXiv …, 2024 - arxiv.org
Antibodies are crucial proteins produced by the immune system to eliminate harmful foreign
substances and have become pivotal therapeutic agents for treating human diseases. To …

Monoclonal Antibodies: Purification, Application in Conventional Methods and Cutting Edge Technology

N Malhotra, A Chahal, A Jain, P Sharma… - Biomedical Materials & …, 2024 - Springer
Antibodies play an important role in health areas such as diagnostic, therapeutic,
vaccination, and prevention. Antibodies were explored by various researchers for various …

[HTML][HTML] Fundamental Considerations of Targeted Drug Therapies for Breast Cancer

I Castillo-Tobías, L Berlanga, J Poblano… - Future …, 2023 - mdpi.com
Breast cancer is a complex disease for which pharmacological treatment does not
guarantee success or cure. In addition, current pharmacological therapies induce unwanted …

[PDF][PDF] Monitoring the charge variant profile of antibody-tomaymycin conjugates by icIEF method

A Abbood - ACTA Pharmaceutica Sciencia, 2023 - actapharmsci.com
This study aimed to evaluate the charge variant profile of antibody-tomaymycin conjugates
using an imaged capillary isoelectric focusing method (icIEF). Two unconjugated antibodies …

Towards a structural and functional analysis of the immunoglobulin-fold proteome.

C Tawfeeq, J Song, U Khaniya, T Madej… - Advances in Protein …, 2024 - europepmc.org
The immunoglobulin fold (Ig fold) domain is a super-secondary structural motif consisting of
a sandwich with two layers of β-sheets that is present in many proteins with very diverse …

[HTML][HTML] Методологические и регуляторные аспекты фармацевтической разработки биопрепаратов

ДВ Куркин, ЕИ Морковин, ДА Бакулин… - Фармация и …, 2024 - pharmpharm.ru
Методологические и регуляторные аспекты фармацевтической разработки биопрепаратов |
Куркин | Фармация и фармакология Фармация и фармакология Farmaciâ i farmakologiâ eng …

Consequences of Immunoglobulin Domain-Containing Protein Retro-Proteins

M Terry, A Hurtado, C Mendoza, L Vargas, I Davila… - 2024 - preprints.org
Amino acid sequences of native proteins are generally not palindromic. The protein
molecule obtained as a result of reading the amino acid sequence backwards, ie, a retro …