[HTML][HTML] Indole-3-propionic acid-aggravated CCl4-induced liver fibrosis via the TGF-β1/Smads signaling pathway

F Liu, C Sun, Y Chen, F Du, Y Yang… - Journal of Clinical and …, 2021 - ncbi.nlm.nih.gov
Methods The liver fibrosis model was established in male C57BL/6 mice by intraperitoneal
injection of CCl 4 twice weekly. IPA intervention was made orally (20 mg/kg daily). The …

Phytochemicals from the cocoa shell modulate mitochondrial function, lipid and glucose metabolism in hepatocytes via activation of FGF21/ERK, AKT, and mTOR …

M Rebollo-Hernanz, Y Aguilera, MA Martin-Cabrejas… - Antioxidants, 2022 - mdpi.com
The cocoa shell is a by-product that may be revalorized as a source of bioactive compounds
to prevent chronic cardiometabolic diseases. This study aimed to investigate the …

Increased adherence to the mediterranean diet after lifestyle intervention improves oxidative and inflammatory status in patients with non-alcoholic fatty liver disease

M Monserrat-Mesquida, M Quetglas-Llabrés, C Bouzas… - Antioxidants, 2022 - mdpi.com
Background: A Mediterranean diet (MedDiet) is recommended as a therapy for non-
alcoholic fatty liver disease (NAFLD) because there is no specific pharmacological treatment …

Effects of cannabidiol on growth performance, appetite, antioxidant capacity and liver inflammatory gene expression of juvenile large yellow croaker (Larmichthys …

Z Wang, X Wang, J Li, Y Gong, Q Li, X Bu, W Lai… - Aquaculture, 2023 - Elsevier
This study evaluated the effects of cannabidiol (CBD) on growth performance, appetite,
antioxidant capacity and liver inflammatory gene expression in juvenile large yellow croaker …

Lactobacillus plantarum LP33 attenuates Pb-induced hepatic injury in rats by reducing oxidative stress and inflammation and promoting Pb excretion

T Hu, J Song, W Zeng, J Li, H Wang, Y Zhang… - Food and Chemical …, 2020 - Elsevier
Lead (Pb) is one of the most common heavy metals and is harmful to human health. The
liver is considered as a major target organ for Pb poisoning. Although probiotics have been …

Mitochondria-targeted antioxidant mitoquinone attenuates liver inflammation and fibrosis in cirrhotic rats

S Turkseven, M Bolognesi, A Brocca… - American Journal …, 2020 - journals.physiology.org
In liver cirrhosis, oxidative stress plays a major role in promoting liver inflammation and
fibrosis. Mitochondria dysregulation is responsible for excessive reactive oxygen species …

Long‐term measures of dyslipidemia, inflammation, and oxidative stress in rats fed a high‐fat/high‐fructose diet

C Feillet‐Coudray, G Fouret, C Vigor, B Bonafos… - Lipids, 2019 - Wiley Online Library
Inflammation and oxidative stress are thought to be involved in, or associated with, the
development of obesity, dyslipidemia, hepatic steatosis, and insulin resistance. This work …

Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades

AS Hendawy, NM El-Lakkany, EM Mantawy… - Life Sciences, 2022 - Elsevier
Aims This study investigates the therapeutic potential of Vilda in a NASH model with liver
fibrosis and elucidates the underlying molecular mechanisms. Main methods To induce …

[HTML][HTML] Interrelation of inflammation and oxidative stress in liver cirrhosis

MM Pomacu, MD Trașcă… - Experimental and …, 2021 - spandidos-publications.com
Recently, the trend of research has been focused on the role of hematological indicators in
assessing the activities of various diseases. The aim of the present study was to determine …

Network pharmacology and molecular docking analysis on molecular targets: Mechanisms of baicalin and baicalein against hyperuricemic nephropathy

H Xiang, H Lei, Z Liu, Y Liu, Y Li, Y Qiu, L Xu - Toxicology and Applied …, 2021 - Elsevier
Oxidative stress and inflammation in kidney are the main causes for hyperuricemic
nephropathy (HN). Baicalin and baicalein, two flavonoids, have anti-inflammatory and anti …