Activating effects of the bioactive compounds from coffee by-products on FGF21 signaling modulate hepatic mitochondrial bioenergetics and energy metabolism in …

M Rebollo-Hernanz, Y Aguilera… - Frontiers in …, 2022 - frontiersin.org
Coffee by-products contain bioactive compounds that have been shown to have the capacity
to modulate human metabolism. The goal of this study was to investigate the effects of the …

Correlation between heavy metal-induced histopathological changes and trophic interactions between different fish species

B Onita, P Albu, H Herman, C Balta, V Lazar, A Fulop… - Applied Sciences, 2021 - mdpi.com
This study assessed the distribution of heavy metals in the gills, kidney, and liver, correlated
with the severity of histopathological changes, of three fish species with different feeding …

[HTML][HTML] Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells

Q Yu, Y Liu, Y Wu, Y Chen - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Aims Curcumin is a polyphenol compound with many pharmacological activities including
antioxidant, lipid-loweing and liver protective. Dihydrocurcumin (DHC) is one of the major …

Metformin ameliorates maternal high-fat diet-induced maternal dysbiosis and fetal liver apoptosis

SW Huang, YC Ou, KS Tang, HR Yu, LT Huang… - Lipids in Health and …, 2021 - Springer
Background The deleterious effect of maternal high-fat diet (HFD) on the fetal rat liver may
cause later development of non-alcoholic fatty liver disease (NAFLD). The aim of this study …

[HTML][HTML] Rutin mitigates hepatic fibrogenesis and inflammation through targeting TLR4 and P2X7 receptor signaling pathway in vitro and in vivo

LS Hou, ZY Cui, P Sun, HQ Piao, X Han, J Song… - Journal of Functional …, 2020 - Elsevier
Rutin is a flavonol glycoside widely existing in plants, used as food antioxidant and
nutritional enhancer. Rutin has vitamin P-like effect and anti-inflammatory effect. This study …

[HTML][HTML] Prognostic value of red blood cell distribution width in hepatocellular carcinoma

H Goyal, ZD Hu - Annals of translational medicine, 2017 - ncbi.nlm.nih.gov
Red blood cell distribution width (RDW) is a simple, inexpensive, routinely measured and
automatically reported blood test parameter, which reflects the degree of anisocytosis of red …

Neferine Exerts Antioxidant and Anti‐Inflammatory Effects on Carbon Tetrachloride‐Induced Liver Fibrosis by Inhibiting the MAPK and NF‐κB/IκBα Pathways

Y Wang, S Wang, R Wang, S Li… - … and Alternative Medicine, 2021 - Wiley Online Library
Reversible liver fibrosis is the consequence of diverse liver injuries. Oxidative stress
combined with inflammation is the primary cause of carbon tetrachloride‐(CCl4‐) induced …

Monitoring physiological processes of fast-growing broilers during the whole life cycle: Changes of redox-homeostasis effected to trassulfuration pathway predicting …

G Pesti-Asbóth, E Szilágyi, P Bíróné Molnár, J Oláh… - Plos one, 2023 - journals.plos.org
In the broiler industry, the average daily gain and feed conversion ratio are extremely
favorable, but the birds are beginning to approach the maximum of their genetic capacity …

Hepatoprotective effects of a functional formula of three Chinese medicinal herbs: experimental evidence and network pharmacology-based identification of …

S Li, N Wang, M Hong, HY Tan, G Pan, Y Feng - Molecules, 2018 - mdpi.com
Various Chinese herbal medicines (CHMs) have shown beneficial liver protection effects.
Jian-Gan-Bao (JGB), a functional herbal formula, consists of three famous CHMs, including …

Synthesis of magnolol and honokiol derivatives and their effect against hepatocarcinoma cells

M Maioli, V Basoli, P Carta, D Fabbri, MA Dettori… - PloS one, 2018 - journals.plos.org
The hepatocellular carcinoma is one of the most common malignant tumour with high level
of mortality rate due to its rapid progression and high resistance to conventional …