Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Psoriasis is a chronic, systemic, immune-mediated disease with an incidence of
approximately 2%. The pathogenesis of the disease is complex and not yet fully understood …

Chemokines and their receptors play an important role in the recruitment, activation and
differentiation of immune cells. The chemokine receptor, CXCR3, and its ligands, CXCL9 …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

In the past decade, we have witnessed considerable developments in understanding the
roles and functions of miRNAs. In parallel, the identification of alterations in miRNA …

Keratinocyte differentiation is an essential process for epidermal stratification and stratum
corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start …

Persistent and impaired inflammation impedes tissue healing and is a characteristic of
chronic wounds. A better understanding of the mechanisms controlling wound inflammation …

Psoriasis is a chronic immune‐mediated inflammatory skin disease that involves a complex
interplay between infiltrated immune cells and keratinocytes. Great progress has been made …

Psoriasis is a chronic immune-mediated skin disease with a significant impact on patients'
quality of life. Mild-to-moderate forms of the disease usually require long-term topical …

Psoriasis is an auto-inflammatory skin disease characterized by abnormal activation of
epidermal keratinocytes, aberrant neovascularization, and dysregulation of immune cells …