Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO3−)
concentration, a secondary decrease in the arterial partial pressure of carbon dioxide …

The serum anion gap, calculated from the electrolytes measured in the chemical laboratory,
is defined as the sum of serum chloride and bicarbonate concentrations subtracted from the …

Lactate is one of the most crucial intermediates in carbohydrate and nonessential amino
acid metabolism. The complexity of cellular interactions and metabolism means that lactate …

Metabolic acidosis is a disorder frequently encountered in emergency medicine and
intensive care medicine. As literature has been enriched with new data concerning the …

The serum anion gap has been utilized to identify errors in the measurement of electrolytes,
to detect paraproteins, and, most relevant to the nephrologist, to evaluate patients with …

Ethylene glycol classically produces an elevated anion gap metabolic acidosis. We report a
series of patients with ethylene glycol toxicity with a component of non‐anion gap metabolic …

Background The ratio of Δ anion gap and Δ bicarbonate (ΔAG/ΔHCO 3) is used to detect
coexisting acid-base disorders in patients with high anion gap metabolic acidosis. Classic …

Background: The ratio of delta anion gap and delta bicarbonate (ΔAG/ΔHCO 3) is used to
detect co-existing acid-base disorders in patients with high anion gap metabolic acidosis …

Carbonic anhydrase (CAII) binds to the electrogenic basolateral Na+-HCO 3− cotransporter
(NBCe1) and facilitates HCO 3− reabsorption across the proximal tubule. However, whether …

The interpretation acid base status is key in medical practice. Primary disorders are
acidemia or alkalemia; and their metabolic or respiratory components are detected via the …