Dictyostelium as host model for pathogenesis
M Steinert, K Heuner - Cellular microbiology, 2005 - Wiley Online Library
The haploid social soil amoeba Dictyostelium discoideum has been established as a host
model for several pathogens including Pseudomonas aeruginosa, Cryptococcus …
model for several pathogens including Pseudomonas aeruginosa, Cryptococcus …
Virulence determinants of the human pathogenic fungus Aspergillus fumigatus protect against soil amoeba predation
F Hillmann, S Novohradská, DJ Mattern… - Environmental …, 2015 - Wiley Online Library
Filamentous fungi represent classical examples for environmentally acquired human
pathogens whose major virulence mechanisms are likely to have emerged long before the …
pathogens whose major virulence mechanisms are likely to have emerged long before the …
Towards a molecular understanding of human diseases using Dictyostelium discoideum
RSB Williams, K Boeckeler, R Gräf… - Trends in molecular …, 2006 - cell.com
The social amoeba Dictyostelium discoideum is increasingly being used as a simple model
for the investigation of problems that are relevant to human health. This article focuses on …
for the investigation of problems that are relevant to human health. This article focuses on …
Macrophage Mediated Immunomodulation During Cryptococcus Pulmonary Infection
Y Wang, S Pawar, O Dutta, K Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Macrophages are key cellular components of innate immunity, acting as the first line of
defense against pathogens to modulate homeostatic and inflammatory responses. They …
defense against pathogens to modulate homeostatic and inflammatory responses. They …
Cryptococcus neoformans Capsular Enlargement and Cellular Gigantism during Galleria mellonella Infection
We have studied infection of Cryptococcus neoformans in the non-vertebrate host Galleria
mellonella with particular interest in the morphological response of the yeast. Inoculation of …
mellonella with particular interest in the morphological response of the yeast. Inoculation of …
Catch me if you can: phagocytosis and killing avoidance by Cryptococcus neoformans
R Garcia-Rodas, O Zaragoza - FEMS Immunology & Medical …, 2012 - academic.oup.com
After inhalation of infectious particles, Cryptococcus neoformans resides in the alveolar
spaces, where it can survive and replicate in the extracellular environment. This yeast has …
spaces, where it can survive and replicate in the extracellular environment. This yeast has …
Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
MS Fu, LC Liporagi-Lopes, SR dos Santos, JL Tenor… - MBio, 2021 - Am Soc Microbiol
Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil
microbes such as Cryptococcus neoformans; these traits can also function in animal …
microbes such as Cryptococcus neoformans; these traits can also function in animal …
Microbial pathogens in the fungal kingdom
J Heitman - Fungal biology reviews, 2011 - Elsevier
The fungal kingdom is vast, spanning∼ 1.5 to as many as 5 million species diverse as
unicellular yeasts, filamentous fungi, mushrooms, lichens, and both plant and animal …
unicellular yeasts, filamentous fungi, mushrooms, lichens, and both plant and animal …
Role of Phagocytosis in the Virulence of Cryptococcus neoformans
M Del Poeta - Eukaryotic cell, 2004 - Am Soc Microbiol
Phagocytosis is a receptor-mediated process that leads to the internalization of foreign
particles into phagocytic cells. Phagocytic cells, such as macrophages, dendritic cells, and …
particles into phagocytic cells. Phagocytic cells, such as macrophages, dendritic cells, and …
The tools for virulence of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
each year. It is believed that most humans are infected with C. neoformans, possibly in a …