The “Amoeboid Predator-Fungal Animal Virulence Hypothesis” posits that interactions with
environmental phagocytes shape the evolution of virulence traits in fungal pathogens. In this …

Cryptococcosis is a life‐threatening fungal disease that infects around one million people
each year. Establishment and progression of disease involves a complex interplay between …

This chapter focuses on the genetic diversity of Cryptococcus species as assessed by
sequence analysis of DNA. In 1935, a comprehensive study was conducted with numerous …

This chapter focuses on the environmental habitats of the dominant human‐pathogenic
species, Cryptococcus neoformans and Cryptococcus gattii, and their varieties and …

Mammalian hosts have traditionally been considered the “gold standard” models for
studying pathogenesis and antifungal drug activity in invasive aspergillosis (IA) …

Listeria monocytogenes can cause severe disease in animal hosts, but it has no recognized
animal host reservoir. We tested the hypothesis that L. monocytogenes retains virulence …

Passage in mice of opportunistic pathogens such as Cryptococcus neoformans is known to
increase virulence, but little is known about the molecular mechanisms involved in virulence …

▪ Abstract To decipher the complexity of host-pathogen interactions the widest possible
range of model hosts and of analytical methods is required. As some virulence mechanisms …

There is an urgent need for new antifungal agents that are both effective and non-toxic in the
therapy of systemic mycoses. The model nematode Caenorhabditis elegans has been used …

Dictyostelium cells are forest soil amoebae, which feed on bacteria and proliferate as
solitary cells until bacteria are consumed. Starvation triggers a change in life style, forcing …