Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap

F Daneshnia, JN de Almeida Júnior, M Ilkit… - The Lancet …, 2023 - thelancet.com
Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

Neglected endemic mycoses

F Queiroz-Telles, AH Fahal, DR Falci… - The Lancet Infectious …, 2017 - thelancet.com
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous
implantation is also an important source of infections. Environmental exposure to spores of …

Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study

AFAD Schauwvlieghe, BJA Rijnders… - The Lancet …, 2018 - thelancet.com
Background Invasive pulmonary aspergillosis typically occurs in an immunocompromised
host. For almost a century, influenza has been known to set up for bacterial superinfections …

Emerging multidrug-resistant Candida species

AL Colombo, JN de Almeida Júnior… - Current Opinion in …, 2017 - journals.lww.com
We checked all papers published along the last 10 years describing epidemiological,
diagnostic, and clinical aspects of infections by MDR Candida spp., with emphasis on C …

The mycobiome in health and disease: emerging concepts, methodologies and challenges

PY Tiew, M Mac Aogain, NABM Ali, KX Thng, K Goh… - Mycopathologia, 2020 - Springer
Fungal disease is an increasingly recognised global clinical challenge associated with high
mortality. Early diagnosis of fungal infection remains problematic due to the poor sensitivity …

Responding to the emergence of antifungal drug resistance: perspectives from the bench and the bedside

J Beardsley, CL Halliday, SCA Chen… - Future …, 2018 - Taylor & Francis
The incidence of serious fungal infections is increasing rapidly, and yet the rate of new drugs
becoming available to treat them is slow. The limited therapeutic armamentarium is a …

PCR-based approach targeting mucorales-specific gene family for diagnosis of mucormycosis

C Baldin, SSM Soliman, HH Jeon… - Journal of Clinical …, 2018 - Am Soc Microbiol
Mucormycosis is an aggressive, life-threatening infection caused by fungi in the order
Mucorales. The current diagnosis of mucormycosis relies on mycological cultures, radiology …

Invasive pulmonary aspergillosis

MP Ledoux, B Guffroy, Y Nivoix… - … in respiratory and …, 2020 - thieme-connect.com
Invasive pulmonary aspergillosis (IPA) remains difficult to diagnose and to treat. Most
common risk factors are prolonged neutropenia, hematopoietic stem cell or solid organ …

[HTML][HTML] The antifungal activity of naphthoquinones: An integrative review

PG FERREIRA, CD NICOLETTI… - Anais da Academia …, 2018 - SciELO Brasil
Naphthoquinones are the most commonly occurring type of quinones in nature. They are a
diverse family of secondary metabolites that occur naturally in plants, lichens and various …

Therapies and vaccines based on nanoparticles for the treatment of systemic fungal infections

B Kischkel, SA Rossi, SR Santos… - Frontiers in cellular …, 2020 - frontiersin.org
Treatment modalities for systemic mycoses are still limited. Currently, the main antifungal
therapeutics include polyenes, azoles, and echinocandins. However, even in the setting of …