The role of mitochondria in rheumatic diseases
The mitochondrion is an intracellular organelle thought to originate from endosymbiosis
between an ancestral eukaryotic cell and an α-proteobacterium. Mitochondria are the …
between an ancestral eukaryotic cell and an α-proteobacterium. Mitochondria are the …
Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?
PL Meroni, MO Borghi, C Grossi… - Nature Reviews …, 2018 - nature.com
Recurrent thrombosis and miscarriages are the main clinical manifestations of
antiphospholipid syndrome (APS). Although most patients display both clinical signs, some …
antiphospholipid syndrome (APS). Although most patients display both clinical signs, some …
[HTML][HTML] Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome
RA Ali, AA Gandhi, HE Meng, S Yalavarthi… - Nature …, 2019 - nature.com
Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which
antiphospholipid antibodies (aPL Abs) effect thrombotic events in patients with …
antiphospholipid antibodies (aPL Abs) effect thrombotic events in patients with …
[HTML][HTML] Pediatric antiphospholipid syndrome
Despite its potential to cause significant morbidity in children, pediatric antiphospholipid
syndrome (APS) is an understudied condition. In this review, we will cover what is known …
syndrome (APS) is an understudied condition. In this review, we will cover what is known …
Identification of mitofusin 1 and complement component 1q subcomponent binding protein as mitochondrial targets in systemic lupus erythematosus
Objective Mitochondria are organelles that exhibit several bacterial features, such as a
double‐stranded genome with hypomethylated CpG islands, formylated proteins, and …
double‐stranded genome with hypomethylated CpG islands, formylated proteins, and …
[HTML][HTML] Clinical characteristics and prognosis of patients with antiphospholipid antibodies based on cluster analysis: an 8-year cohort study
W Qi, J Zhao, C Huang, N Jiang, J Li, C Wu… - Arthritis Research & …, 2022 - Springer
Background Antiphospholipid syndrome (APS) is an autoimmune disease characterized by
persistent antiphospholipid antibodies (aPLs) positivity with a wide manifestation spectrum …
persistent antiphospholipid antibodies (aPLs) positivity with a wide manifestation spectrum …
[HTML][HTML] The issue of the antiphospholipid antibody syndrome
DC Oliveira, A Correia, C Oliveira - Journal of clinical medicine …, 2020 - ncbi.nlm.nih.gov
Antiphospholipid antibody syndrome (APS) is a state of hypercoagulability secondary to an
autoimmune disorder. It is associated with thrombotic events in venous and arterial vessels …
autoimmune disorder. It is associated with thrombotic events in venous and arterial vessels …
[HTML][HTML] Adenosine diphosphate‐induced aggregation is enhanced in platelets obtained from patients with thrombotic primary antiphospholipid syndrome (t‐PAPS) …
Background Thrombotic antiphospholipid syndrome (t‐PAPS) is characterized by arterial,
venous, or microvascular occlusions, which are explained, in part, by the presence of …
venous, or microvascular occlusions, which are explained, in part, by the presence of …
[HTML][HTML] Managing antiphospholipid syndrome in children and adolescents: current and future prospects
AG Islabao, VC Trindade, LMH da Mota, DCO Andrade… - Pediatric Drugs, 2022 - Springer
Pediatric antiphospholipid syndrome (APS) is a rare acquired multisystem autoimmune
thromboinflammatory condition characterized by thrombotic and non-thrombotic clinical …
thromboinflammatory condition characterized by thrombotic and non-thrombotic clinical …
[HTML][HTML] Non-criteria antiphospholipid antibodies and pediatric rheumatic disease: a case series
SA Mahmud, DR Bullock, CK Correll, PM Hobday… - Pediatric …, 2022 - Springer
Background Non-criteria antiphospholipid antibodies (NC-aPL) are a relatively undefined
subgroup of antiphospholipid antibodies (aPL). Knowledge about NC-aPL in adults is …
subgroup of antiphospholipid antibodies (aPL). Knowledge about NC-aPL in adults is …