Matrix metalloproteinases shape the tumor microenvironment in cancer progression

S Niland, AX Riscanevo, JA Eble - International journal of molecular …, 2021 - mdpi.com
Cancer progression with uncontrolled tumor growth, local invasion, and metastasis depends
largely on the proteolytic activity of numerous matrix metalloproteinases (MMPs), which …

The role of matrix metalloproteinases (MMP-8, MMP-9, MMP-13) in periodontal and peri-implant pathological processes

I Luchian, A Goriuc, D Sandu, M Covasa - International Journal of …, 2022 - mdpi.com
Severe periodontitis, a destructive inflammatory disease of the supporting tissues of the
teeth, ranks sixth in terms of global spread, affecting about 11% of the population …

The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities

CM Neophytou, M Panagi, T Stylianopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Metastasis, the process by which cancer cells escape primary tumor site
and colonize distant organs, is responsible for most cancer-related deaths. The tumor …

[HTML][HTML] Myricetin: A review of the most recent research

X Song, L Tan, M Wang, C Ren, C Guo, B Yang… - Biomedicine & …, 2021 - Elsevier
Myricetin (MYR) is a flavonoid compound widely found in many natural plants including
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …

Decoding leader cells in collective cancer invasion

SA Vilchez Mercedes, F Bocci, H Levine… - Nature Reviews …, 2021 - nature.com
Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

Pharmacological properties and derivatives of shikonin—A review in recent years

C Guo, J He, X Song, L Tan, M Wang, P Jiang… - Pharmacological …, 2019 - Elsevier
Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunity

M Gómez-Herranz, J Taylor, RD Sloan - Journal of Biological Chemistry, 2023 - ASBMB
Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Extracellular matrix alterations in metastatic processes

M Paolillo, S Schinelli - International journal of molecular sciences, 2019 - mdpi.com
The extracellular matrix (ECM) is a complex network of extracellular-secreted
macromolecules, such as collagen, enzymes and glycoproteins, whose main functions deal …

Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct

L Su, D Jin, Y Wang, Q Wang, C Pan, S Jiang… - Science …, 2023 - science.org
The magnetic microrobots promise benefits in minimally invasive cell-based therapy.
However, they generally suffer from an inevitable compromise between their magnetic …

Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms

A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …