MicroRNA dysregulations in Merkel cell carcinoma: Molecular mechanisms and clinical applications

C Mazziotta, CF Cervellera, C Lanzillotti… - Journal of Medical …, 2023 - Wiley Online Library
Merkel cell carcinoma (MCC) is an aggressive skin malignancy with two distinct etiologies.
The first, which accounts for the highest proportion, is caused by Merkel cell polyomavirus …

Tumor associated macrophage in HPV+ tumors: Between immunosuppression and inflammation

L Gorvel, D Olive - Seminars in immunology, 2023 - Elsevier
Over the past few decades, with the rise of immunotherapies, tumor infiltrating immune cells
were increasingly investigated. Indeed, they may represent biomarkers for patient outcome …

[HTML][HTML] Human papillomavirus epidemiology and prevention: is there still a gender gap?

G Milano, G Guarducci, N Nante, E Montomoli, I Manini - Vaccines, 2023 - mdpi.com
Background and aim: Human papillomavirus (HPV) is sexually transmitted, one of the three
most common sexually transmitted infections (STIs) in both males and females, and the most …

[HTML][HTML] Integration of scRNA-Seq and TCGA RNA-Seq to analyze the heterogeneity of HPV+ and HPV-cervical cancer immune cells and establish molecular risk …

E Wei, A Reisinger, J Li, LE French… - Frontiers in …, 2022 - frontiersin.org
Background Numerous studies support that Human papillomavirus (HPV) can cause
cervical cancer. However, few studies have surveyed the heterogeneity of HPV infected or …

[HTML][HTML] miRNA in molecular diagnostics

M Matulić, P Gršković, A Petrović, V Begić, S Harabajsa… - Bioengineering, 2022 - mdpi.com
MicroRNAs are a class of small non-coding RNA molecules that regulate gene expression
on post-transcriptional level. Their biogenesis consists of a complex series of sequential …

[HTML][HTML] E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

MR Patterson, AS Meijers, EL Ryder, LM Wootton… - Oncogene, 2024 - nature.com
Human papillomaviruses (HPV) are a major cause of malignancy, contributing to~ 5% of all
human cancers worldwide, including most cervical cancer cases and a growing number of …

[HTML][HTML] Multiple HPV integration mode in the cell lines based on long-reads sequencing

X Cui, Y Li, C Zhang, Y Qi, Y Sun, W Li - Frontiers in Microbiology, 2023 - frontiersin.org
Background The integration of human papillomavirus (HPV) is closely related to the
occurrence of cervical cancer. However, little is known about the complete state of HPV …

[HTML][HTML] The mechanisms and diagnostic potential of lncRNAs, miRNAs, and their related signaling pathways in cervical cancer

Y Xu, Y Sun, X Song, J Ren - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Cervical cancer (CC), the fourth most prevalent type of cancer among women worldwide, is
associated with high rates of morbidity and mortality. Due to the long period of latency in CC …

[HTML][HTML] Metal-based approaches to fight cervical cancer

D Pereira, N Alves, Â Sousa, JFA Valente - Drug Discovery Today, 2024 - Elsevier
Cervical cancer (CC) is one of the leading causes of death among women worldwide. The
current treatments for this cancer consist of invasive methods such as chemotherapeutic …

Quantitative Proteomics Reveal the Mechanism of MiR-138–5p Suppressing Cervical Cancer via Targeting ZNF385A

Q Peng, Y Deng, G Li, J Li, P Zheng… - Journal of Proteome …, 2024 - ACS Publications
MicroRNAs are short, noncoding RNA molecules that exert pivotal roles in cancer
development and progression by modulating various target genes. There is growing …