LH and chorionic gonadotropin (CG) are glycoproteins fundamental to sexual development
and reproduction. Because they act on the same receptor (LHCGR), the general consensus …

This review summarizes the important role of Anti-Müllerian hormone (Amh) during gonad
development in fishes. This Tgfβ-domain bearing hormone was named after one of its …

Gonadotropins are primary hormones that control vertebrate reproduction. In a recent study,
we analyzed the impacts of FSH and LH on zebrafish reproduction by disrupting FSH and …

Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We
investigate the effects of Igf3, a fish-specific member of the igf family. Fsh increased in a …

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors, initially
described as molecular targets for synthetic compounds inducing peroxisome proliferation …

Background Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and
reside within a specific microenvironment in the testes called “niche” which regulates stem …

The utilization of zebrafish in biomedical research is very common in the research world
nowadays. Today, it has emerged as a favored vertebrate organism for the research in …

Estrogen plays an important role in many physiological events including carcinogenesis and
the development of human breast cancer. However, the molecular mechanisms of estrogen …

Polycystic ovarian syndrome (PCOS) causes swollen ovaries in women at reproductive age
due to hormonal disorder with small cysts on the outer edges. The cause of the disorder is …

It is well established in various experimental models that luteinizing hormone (LH)
stimulated testosterone (T) production of Leydig cells is the key endocrine stimulus of …