Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …

Dendrobium officinale polysaccharide (DOP) has received an increasing amount of attention
as it could alleviate AD-related cognitive impairment via the regulation of microglial …

Symptomatic interventions for patients with dementia involve anti-dementia drugs to improve
cognition, psychotropic drugs for the treatment of behavioral disorders (BDs), and different …

Alzheimer's disease (AD) is the most common neurodegenerative disorder with the majority
of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved …

Sleep disorders are common in patients with Alzheimer's disease, and can even occur in
patients with amnestic mild cognitive impairment, which appears before Alzheimer's …

The association between Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) has
been extensively demonstrated, but despite this, the pathophysiological mechanisms …

Circadian dysfunction has been described in patients with symptomatic Alzheimer's disease
(AD), as well as in presymptomatic phases of the disease. Modeling this circadian …

Background: The choroid plexus (CP), which constitutes the blood-cerebrospinal fluid
barrier, was recently identified as an important component of the circadian clock system …

The choroid plexus (CP) is part of the blood‐cerebrospinal fluid barrier (BCSFB) and was
recently described as an important component of the circadian clock system. It is the …