Engineering Single‐Atom Nanozymes for Catalytic Biomedical Applications

Y Zhu, Y Liao, J Zou, J Cheng, Y Pan, L Lin, X Chen - Small, 2023 - Wiley Online Library
Nanomaterials with enzyme‐mimicking properties, coined as nanozymes, are a promising
alternative to natural enzymes owing to their remarkable advantages, such as high stability …

Biomedicine meets nanozyme catalytic chemistry

C Cao, N Yang, X Wang, J Shao, X Song… - Coordination Chemistry …, 2023 - Elsevier
Nanozymes, tiny-sized artificial enzymes, hold promise in mimicking the catalytic actions of
natural enzymes. The intersection between nanozyme and biomedicine has sparked …

Self‐Driven Electricity Modulates d‐Band Electrons of Copper Single‐Atom Nanozyme for Boosting Cancer Therapy

S Zhong, C Xiong, Y Zhao, S Yao, Q Hu… - Advanced Functional …, 2023 - Wiley Online Library
Single‐atom nanozymes (SAzymes) are considered as the most promising candidates for
natural enzymes due to their atomically dispersed active sites that closely resemble the …

Intrinsic strain-mediated ultrathin ceria nanoantioxidant

C Liu, L Gui, JJ Zheng, YQ Xu, B Song… - Journal of the …, 2023 - ACS Publications
Metal oxide nanozymes have emerged as the most efficient and promising candidates to
mimic antioxidant enzymes for treatment of oxidative stress-mediated pathophysiological …

[HTML][HTML] The applications of nanozymes in neurological diseases: from mechanism to design

Y Zhang, L Zhang, M Wang, P Li - Theranostics, 2023 - ncbi.nlm.nih.gov
Nanozymes are a class of nanomaterials with enzyme-like catalytic activities. Due to their
multiple catalytic activities, as well as their good stability, modifiable activity and other …

[HTML][HTML] MOF-derived bimetallic nanozyme to catalyze ROS scavenging for protection of myocardial injury

K Xiang, H Wu, Y Liu, S Wang, X Li, B Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Myocardial injury triggers intense oxidative stress, inflammatory response, and
cytokine release, which are essential for myocardial repair and remodeling. Excess reactive …

Microenvironment-Responsive Metal-Phenolic Nanozyme Release Platform with Antibacterial, ROS Scavenging, and Osteogenesis for Periodontitis

Y Xu, Y Luo, Z Weng, H Xu, W Zhang, Q Li, H Liu… - ACS …, 2023 - ACS Publications
Periodontitis is a chronic inflammatory disease deriving from dental plaque, characterized by
the excessive accumulation of reactive oxygen species (ROS), matrix metalloproteinase …

Colorimetric sensing of biomarkers based on the enzyme-mimetic activity of metal nanoclusters

N Gao, J Xu, X Li, G Ling, P Zhang - Chemical Engineering Journal, 2023 - Elsevier
Metal nanoclusters (MNCs) less than 10 nm in size have emerged as exciting functional
nanomaterials. As a new generation of artificial mimetic enzymes, they exhibit similar …

Bifunctional Cascading Nanozymes Based on Carbon Dots Promotes Photodynamic Therapy by Regulating Hypoxia and Glycolysis

T Luo, H Yang, R Wang, Y Pu, Z Cai, Y Zhao, Q Bi… - ACS …, 2023 - ACS Publications
Photodynamic therapy (PDT) still faces great challenges with suitable photosensitizers,
oxygen supply, and reactive oxygen species (ROS) accumulation, especially in the tumor …

Nanozyme-Integrated Thermoresponsive In Situ Forming Hydrogel Enhances Mesenchymal Stem Cell Viability and Paracrine Effect for Efficient Spinal Cord Repair

L Xu, J Mu, Z Ma, P Lin, F Xia, X Hu, J Wu… - … Applied Materials & …, 2023 - ACS Publications
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising strategy for the
treatment of spinal cord injury (SCI). However, the hostile microenvironment of SCI, which …