Versatile strategies have been developed to construct electrospun fiber-based drug delivery
systems for tissue regeneration and cancer therapy. We first introduce the construction of …

The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Electrical stimulation is a promising strategy for treating neural diseases. However, current
energy suppliers cannot provide effective power for in situ electrical stimulation. Here, an …

Electrospinning (e‐spin) technique has emerged as a versatile and feasible pathway for
constructing diverse polymeric fabric structures, which show potential applications in many …

Neural stem cells (NSCs) are considered to be prospective replacements for neuronal cell
loss as a result of spinal cord injury (SCI). However, the survival and neuronal differentiation …

Due to the complex structural hierarchy and regenerative microenvironment of peripheral
nerves, developing a nerve guidance conduit (NGC) that can replace autografts for repairing …

Anisotropic topographies and biological cues can simulate the regenerative
microenvironment of nerve from physical and biological aspects, which show promising …

Electrospinning is a popular and effective method of producing porous nanofibers with a
large surface area, superior physical and chemical properties, and a controllable pore size …

Nerve guidance conduits with hollow lumen fail to regenerate critical-sized peripheral nerve
defects (15 mm in rats and 25 mm in humans), which can be improved by a beneficial …

Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …