Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids

O Tartagni, A Borók, E Mensà, A Bonyár… - Cellular and Molecular …, 2023 - Springer
Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with
respect to more traditional 2D culturing. Microwell culturing is a simple and accessible …

[HTML][HTML] Effects and mechanisms of action of preussin, a marine fungal metabolite, against the triple-negative breast cancer cell line, MDA-MB-231, in 2D and 3D …

R Seabra, F Malhão, A Correia, C Costa, A Kijjoa… - Marine Drugs, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer
(BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic …

[HTML][HTML] Immune microenvironment dynamics of HER2 overexpressing breast cancer under dual anti-HER2 blockade

S Batalha, CM Gomes, C Brito - Frontiers in Immunology, 2023 - frontiersin.org
Introduction The clinical prognosis of the HER2-overexpressing (HER2-OE) subtype of
breast cancer (BC) is influenced by the immune infiltrate of the tumor. Specifically, monocytic …

3D co-culture of macrophages and fibroblasts in a sessile drop array for unveiling the role of macrophages in skin wound-healing

X Lyu, F Cui, H Zhou, B Cao, X Zhang, M Cai… - Biosensors and …, 2023 - Elsevier
Abstract Three-dimensional (3D) heterotypic multicellular spheroid models play important
roles in researches of the proliferation and remodeling phases in wound healing. This study …

Mapping Cell-in-Cell Structures in Oral Squamous Cell Carcinoma

LO Siquara da Rocha, BSF Souza, RD Coletta… - Cells, 2023 - mdpi.com
Cell-in-cell (CIC) structures contribute to tumor aggressiveness and poor prognosis in oral
squamous cell carcinoma (OSCC). In vitro 3D models may contribute to the understanding of …

A Step Forward in the Characterization of Primary Brown Trout Hepatocytic Spheroids as Experimental Models

RF Alves, C Lopes, E Rocha, TV Madureira - Animals, 2023 - mdpi.com
Simple Summary The liver is a vital organ for xenobiotic biotransformation and a prime
target for drug toxicity. The search for alternative experimental liver models in fish and other …

In Vitro Comparison of Three-Dimensional Cultured Periodontal Ligament Stem Cells Derived from Permanent and Supernumerary Teeth

H Kim, KE Lee, YK Chae, OH Nam, MS Kim, JH Jang… - Applied Sciences, 2023 - mdpi.com
The characteristics of 3-dimensional (3D) cultured periodontal ligament stem cells derived
from permanent teeth (pPDLSCs) and supernumerary teeth (sPDLSCs) were compared and …

3D co-culture of macrophages and fibroblasts in a sessile drop chip for unveiling the role of macrophages in skin wound-healing

X Lyu, F Cui, H Zhou, B Cao, M Cai, S Yang, B Sun… - bioRxiv, 2023 - biorxiv.org
Abstract Three-dimension (3D) cell co-cultural spheroids exhibit enhanced cellular functions
and they can mirror in-vivo microenvironments. Herein, a sessile drop chip was developed …

Mapping cell-in-cell structures in oral squamous cell carcinoma

LOS Rocha, BSF Souza, RD Coletta, DW Lambert… - 2023 - arca.fiocruz.br
Abstract Cell-in-cell (CIC) structures contribute to tumor aggressiveness and poor prognosis
in oral squamous cell carcinoma (OSCC). In vitro 3D models may contribute to the …

3 차원세포배양을위한헥사노일글리콜키토산기반세포비부착성메쉬-패턴배양접시설계및성능평가

구은영, 박경환, 강선웅, 허강무 - 폴리머, 2023 - dbpia.co.kr
삼차원 스페로이드 세포배양은 기존 2 차원 세포배양보다 높은 생체유사성으로 약물 스크리닝,
세포치료제 및 조직재생 등 다양한 바이오메디컬 연구에서 광범위하게 활용되고 있다. 본 …