Acid‐base alterations in patients with kidney failure and on hemodialysis (HD) treatment
contribute to (1) intradialytic hypercapnia and hypoxia,(2) hemodynamic instability and …

Background A novel in vitro test (T50 test) assesses ex vivo serum calcification propensity
and predicts mortality in chronic kidney disease and haemodialysis (HD) patients. For the …

Introduction Abnormalities in blood bicarbonates (HCO3–) concentration are a common
finding in patients with chronic kidney disease, especially at the end-stage renal failure …

Acid-base and electrolyte alterations are common in patients with chronic kidney disease
(CKD) and end-stage kidney failure (ESRD). The alterations become more complex as CKD …

The use of high dialysate bicarbonate for hemodialysis in end-stage renal disease is
associated with increased mortality, but potential physiological mediators are poorly …

Acetate is an important metabolite in metabolic fluxes. Its presence in biological entities
originates from both exogenous inputs and endogenous metabolism. Because the change …

Background: It is unclear whether the use of higher dialysate bicarbonate concentrations is
associated with clinically relevant changes in the pre-dialysis serum bicarbonate …

Introduction The validity of adjusting dialysate bicarbonate based on pre‐hemodialysis (HD)
serum bicarbonate is unclear. There are no studies of the impact of dialysate sodium on …

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Metabolic alkalosis, a disorder that causes elevations in serum bicarbonate and arterial pH,
is a common metabolic abnormality found in nearly half of hospitalized patients but is rare in …