Interferon-γ and infectious diseases: Lessons and prospects

JL Casanova, JD MacMicking, CF Nathan - Science, 2024 - science.org
Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …

The translational potential of studying bat immunity

K Baid, AT Irving, N Jouvenet, A Banerjee - Trends in Immunology, 2024 - cell.com
Molecular studies in bats have led to the discovery of antiviral adaptations that may explain
how some bat species have evolved enhanced immune tolerance towards viruses …

Evolution of guanylate binding protein genes shows a remarkable variability within bats (Chiroptera)

A Pinheiro, JR Borges, JV Côrte-Real… - Frontiers in …, 2024 - frontiersin.org
Background GBP s (guanylate binding proteins), an evolutionary ancient protein family, play
a key role in the host's innate immune response against bacterial, parasitic and viral …

Alternative splicing expands the antiviral IFITM repertoire in Chinese horseshoe bats

N Mak, D Zhang, X Li, K Rahman, SAK Datta, J Taylor… - bioRxiv, 2023 - biorxiv.org
The interferon response is shaped by the evolutionary arms race between hosts and the
pathogens they carry. The human interferon-induced transmembrane protein (IFITM) family …