Mastocytosis (M) represents a systemic pathology characterized by increased accumulation
and clonal proliferation of mast cells in the skin and/or different organs. Broadly, M is …

Abstract Peutz‑Jeghers syndrome (PJS), a rare autosomal dominant serine/threonine kinase
11 (STK11)/liver kinase B1 (LKB1) gene‑related genodermatosis, is characterized by oral …

Primary hyperparathyroidism (PHPT), an endocrine condition caused by a parathyroid
adenoma (PTA) in 80‑85% of the cases, has shifted in the modern era to a mildly …

Neuroendocrine neoplasms (NENs) are a group of heterogeneous tumors with
neuroendocrine differentiation that can arise from any organ. They account for 2% of all …

Ganglioneuroma, a rare neural crest‑derived tumor, exhibits a benign profile in contrast to
other neuroblastic tumors (neuroblastoma/ganglioneuroblastoma). Ganglioneuromas can …

Simple Summary Although pancreatic neuroendocrine neoplasms represent less than 5% of
all pancreatic cancers, their incidence rate has risen dramatically over the last decade …

Li‑Fraumeni syndrome (LFS) is a cancer‑prone, autosomal dominant syndrome caused by
underlying germline gene mutations of TP53, a tumor‑suppressor gene encoding the p53 …

Acromegaly is a hormonal disorder which occurs as the result of growth hormone (GH) and
insulin growth factor 1 (IGF‑1) over‑secretion; both hormones are related to skin anomalies …

Abstract Carney complex (CΝC) is a very rare, autosomal dominant, hereditary syndrome.
Seventy percent of individuals with CNC have germline inactivating or deleting mutations of …

The mechanism by which multiple types of endocrine disorders and diseases cause
diabetes reflects activation of stress hormones, including growth hormone (GH) …