[HTML][HTML] A snapshot on the cis chromatin response to DNA double-strand breaks
T Clouaire, G Legube - Trends in Genetics, 2019 - cell.com
In eukaryotes, detection and repair of DNA double-strand breaks (DSBs) operate within
chromatin, an incredibly complex structure that tightly packages and regulates DNA …
chromatin, an incredibly complex structure that tightly packages and regulates DNA …
The tale of a tail: histone H4 acetylation and the repair of DNA breaks
S Dhar, O Gursoy-Yuzugullu… - … Transactions of the …, 2017 - royalsocietypublishing.org
The ability of cells to detect and repair DNA double-strand breaks (DSBs) within the complex
architecture of the genome requires co-ordination between the DNA repair machinery and …
architecture of the genome requires co-ordination between the DNA repair machinery and …
Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+ T Cells
DA Kulpa, A Talla, JH Brehm, SP Ribeiro… - Journal of …, 2019 - Am Soc Microbiol
During antiretroviral therapy (ART), human immunodeficiency virus type 1 (HIV-1) persists
as a latent reservoir in CD4+ T cell subsets in central memory (TCM), transitional memory …
as a latent reservoir in CD4+ T cell subsets in central memory (TCM), transitional memory …
Sentinels of chromatin: chromodomain helicase DNA-binding proteins in development and disease
A Alendar, A Berns - Genes & Development, 2021 - genesdev.cshlp.org
Chromatin is highly dynamic, undergoing continuous global changes in its structure and
type of histone and DNA modifications governed by processes such as transcription, repair …
type of histone and DNA modifications governed by processes such as transcription, repair …
[HTML][HTML] DNA double-strand break repair: Putting zinc fingers on the sore spot
JK Singh, H van Attikum - Seminars in Cell & Developmental Biology, 2021 - Elsevier
Abstract Zinc-Finger (ZnF) proteins represent one of the most abundant group of proteins in
the human genome. At first characterized as DNA binding proteins, it has become …
the human genome. At first characterized as DNA binding proteins, it has become …
[HTML][HTML] CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
Chromatin structure is dynamically reorganized at multiple levels in response to DNA double-
strand breaks (DSBs). Yet, how the different steps of chromatin reorganization are …
strand breaks (DSBs). Yet, how the different steps of chromatin reorganization are …
SUMO, a small, but powerful, regulator of double-strand break repair
AJ Garvin, JR Morris - … of the Royal Society B: Biological …, 2017 - royalsocietypublishing.org
The response to a DNA double-stranded break in mammalian cells is a process of sensing
and signalling the lesion. It results in halting the cell cycle and local transcription and in the …
and signalling the lesion. It results in halting the cell cycle and local transcription and in the …
ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses
ND Berger, FKT Stanley, S Moore… - … Transactions of the …, 2017 - royalsocietypublishing.org
Ataxia-telangiectasia mutated (ATM) is a serine/threonine protein kinase with a master
regulatory function in the DNA damage response. In this role, ATM commands a complex …
regulatory function in the DNA damage response. In this role, ATM commands a complex …
[HTML][HTML] Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
ER Wonderlich, K Subramanian, B Cox… - PLoS …, 2019 - journals.plos.org
Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as
the virus rebounds within a few weeks upon treatment interruption. Viral rebound may be …
the virus rebounds within a few weeks upon treatment interruption. Viral rebound may be …