Characterizations of myosin essential light chain's N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to …

L Wang, P Muthu, D Szczesna-Cordary… - Journal of muscle …, 2013 - Springer
Cross-bridge kinetics were studied at 20° C in cardiac muscle strips from transgenic (Tg)
mice expressing N-terminal 43 amino acid truncation mutation (Δ43) of myosin essential …

Phosphorylation of cMyBP-C affects contractile mechanisms in a site-specific manner

L Wang, X Ji, D Barefield, S Sadayappan, M Kawai - Biophysical journal, 2014 - cell.com
Cardiac myosin binding protein-C (cMyBP-C) is a cardiac-specific, thick-filament regulatory
protein that is differentially phosphorylated at Ser 273, Ser 282, and Ser 302 by various …

Increased coronary venous inorganic phosphate concentrations during experimental myocardial ischemia

LH Opie, M Thomas, P Owen, G Shulman - The American Journal of …, 1972 - Elsevier
The concentration of inorganic phosphate in coronary venous blood draining the ischemic
myocardium is increased. After coronary arterial ligation (46 dogs, thoracotomy), the mean …

Exogenous substrate effects on endogenous lipid metabolism in the working rat heart

MF Crass III - Biochimica et Biophysica Acta (BBA)-Lipids and Lipid …, 1972 - Elsevier
1. The possible regulation of endogenous lipid utilization by exogenous substrates was
studied in a more physiological perfused working rat heart preparation. 2. 2. Rat hearts were …

Diversity and similarity of motor function and cross-bridge kinetics in papillary muscles of transgenic mice carrying myosin regulatory light chain mutations D166V and …

L Wang, P Muthu, D Szczesna-Cordary… - Journal of molecular and …, 2013 - Elsevier
Mechanical properties of skinned papillary muscle fibers from transgenic mice expressing
familial hypertrophic cardiomyopathy associated mutations D166V and R58Q in myosin …

Effects of insulin and work on fructose 2, 6-bisphosphate content and phosphofructokinase activity in perfused rat hearts.

JW Lawson, K Uyeda - Journal of Biological Chemistry, 1987 - ASBMB
The effects of insulin and increased cardiac work on glycolytic rate, metabolite content, and
fructose 2, 6-bisphosphate (Fru-2, 6-P2) content were studied in isolated perfused rat hearts …

Cardiac function and responsiveness to beta-adrenoceptor agonists in rats with obstructive jaundice

G Jacob, N Nassar, G Hayam… - American Journal …, 1993 - journals.physiology.org
The function and role of the heart and the contribution of cardiac beta-adrenoceptors in the
pathogenesis of circulatory failure in obstructive jaundice were studied in the 3-day bile duct …

Evidence for improved myocardial oxygen delivery and function during hypoxia in the mole rat

Y Edoute, R Arieli, E Nevo - Journal of Comparative Physiology B, 1988 - Springer
The high capillary density of the hypoxic adapted mole rat may provide an efficient oxygen
extraction system that permits the maintenance of a normal metabolic rate during hypoxia …

Effect of beta-adrenergic blockade on biochemical and metabolic response to exercise

LH Opie - The American Journal of Cardiology, 1985 - Elsevier
During normal exercise the myocardium, skeletal muscle, liver and adipose tissue all
participate in the metabolic response to exercise. Beta-blockade, by impairing this …

Effects of metformin on glucose uptake by isolated diaphragm from normal and diabetic rats

KN Frayn, PI Adnitt - Biochemical pharmacology, 1972 - Elsevier
The effects of the antidiabetic drug metformin (Nl, Nl-dimethylbiguanide) on glucose uptake
by isolated rat diaphragm muscle have been studied. A therapeutic concentration of …