Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

A growing body of evidence highlights the properties of flavonoids in natural foods for
disease prevention. Due to their antioxidative, anti-inflammatory, and anti-carcinogenic …

The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Summary Background Benefits of Intermittent fasting (IF) on health-related outcomes have
been found in a range of randomised controlled trials (RCTs). Our umbrella review aimed to …

This study investigated the ability of 6-shogaol to reduce obesity in C57BL/6J mice fed with
high-fat diet (HFD). After 12 weeks of 6-shogaol (20, 40, 60 mg/kg/2 days) intervention …

Obesity and its complications have become serious global health concerns recently and
increasing work has been carried out to explicate the underlying mechanism of the disease …

As a multi-potency cytokine, leptin not only plays a crucial role in controlling weight and
energy homeostasis but also participates in the metabolic balance in the human body …

Background Chronically elevated free fatty acid levels can adversely affect pancreatic β-
cells, leading to insulin resistance and eventually type 2 diabetes mellitus (T2DM). Polydatin …

Oleanolic acid (OA) is a natural triterpene widely found in olive leaves that possesses
antioxidant, anti-inflammatory, and insulin-sensitizing properties, among others. These OA …

Background Insulin resistance (IR) and obesity are risk factors for hypertension; triglyceride-
glucose (TyG) is known as a surrogate for IR. The present study investigated the association …