Should ebselen be considered for the treatment of mercury intoxication? A minireview
Mercury is a ubiquitous environmental contaminant and can be found in inorganic (Hg0,
Hg+ and Hg2+) and organic forms (chiefly CH3Hg+ or MeHg+). The main route of human …
Hg+ and Hg2+) and organic forms (chiefly CH3Hg+ or MeHg+). The main route of human …
Highly Electrophilic Intermediates in the Bypass Mechanism of Glutathione Peroxidase: Synthesis, Reactivity, and Structures of Selenocysteine‐Derived Cyclic …
R Masuda, T Karasaki, S Sase… - … –A European Journal, 2023 - Wiley Online Library
Selenocysteine (Sec)‐derived cyclic selenenyl amides, formed by the intramolecular
cyclization of Sec selenenic acids (Sec–SeOHs), have been postulated to function as …
cyclization of Sec selenenic acids (Sec–SeOHs), have been postulated to function as …
Organoselenium compounds in medicinal chemistry
C Gallo-Rodriguez, JB Rodriguez - ChemMedChem, 2024 - Wiley Online Library
The chemical and biological interest in this element and the molecules bearing selenium
has been exponentially growing over the years. Selenium, formerly designated as a toxin …
has been exponentially growing over the years. Selenium, formerly designated as a toxin …
Synthesis and glutathione peroxidase (GPx)-like activity of selenocystine (SeC) bioconjugates of biotin and lipoic acid
SK Maurya, A Tripathi, S Karuthapandi, HB Singh - Amino Acids, 2023 - Springer
The conjugation of active biomolecules provides insight into their bioreactivity, leading to
many applications in biotechnology and materials science. Herein, we report L …
many applications in biotechnology and materials science. Herein, we report L …
[HTML][HTML] A selenoureido-iminoglycolipid transported by zeolitic-imidazolate framework nanoparticles: a novel antioxidant therapeutic approach
F Guerrero, A Carmona, V Vidal, A Franco… - Nanoscale …, 2023 - pubs.rsc.org
A selenium-containing metal–organic framework with remarkable antioxidant capacity and
ROS-scavenging activity was constructed by a controlled de novo encapsulation approach …
ROS-scavenging activity was constructed by a controlled de novo encapsulation approach …
[HTML][HTML] Identification of sulfhydryl-containing proteins and further evaluation of the selenium-tagged redox homeostasis-regulating proteins
Z Jiang, Y Tang, J Lu, C Xu, Y Niu, G Zhang, Y Yang… - Redox Biology, 2024 - Elsevier
Chemoproteomic profiling of sulfhydryl-containing proteins has consistently been an
attractive research hotspot. However, there remains a dearth of probes that are specifically …
attractive research hotspot. However, there remains a dearth of probes that are specifically …
[HTML][HTML] Antioxidant Chimeric Molecules: Are Chemical Motifs Additive? The Case of a Selenium-Based Ligand
D Zeppilli, A Aldinio-Colbachini, G Ribaudo… - International Journal of …, 2023 - mdpi.com
We set up an in silico experiment and designed a chimeric compound integrating molecular
features from different efficient ROS (Reactive Oxygen Species) scavengers, with the …
features from different efficient ROS (Reactive Oxygen Species) scavengers, with the …