Heme oxygenases (HOs) are the rate-limiting enzymes in the catabolism of heme into
biliverdin, free iron, and carbon monoxide. Two genetically distinct isoforms of HO have …

The dipeptide carnosine has been observed to exert antiaging activity at cellular and whole
animal levels. This review discusses the possible mechanisms by which carnosine may …

Background Curcumin has been demonstrated to have many neuroprotective properties,
including improvement of cognition in humans and neurogenesis in animals, yet the …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by memory loss, cognitive impairment, and functional decline leading to dementia and …

Modulation of endogenous cellular defense mechanisms via the vitagene system represents
an innovative approach to therapeutic intervention in diseases causing chronic tissue …

Oxidative stress is a major component of harmful cascades activated in neurodegenerative
disorders. We sought to elucidate possible effects of alginate oligosaccharide (AOS) on H 2 …

The identification of bioactive molecules that have potential to interrupt carcinogenesis
continues to garner research interest. In particular, molecules that have dietary origin are …

Hydrogen sulfide (H2S) is an essential physiological product in brain. We investigated the
expression of cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CGL), the two H2S …

1. ABSTRACT A large body of evidence points to the positive effects of dietary
supplementation of acetyl-L-carnitine (ALC). Its use has shown health benefits in …

Resveratrol, a polyphenol presents in grapes and wine, displays antioxidant and anti-
inflammatory properties and cytoprotective effect in brain pathologies associated to oxidative …