Curcumin induces stress response and hormetically modulates wound healing ability of human skin fibroblasts undergoing ageing in vitro

D Demirovic, SIS Rattan - Biogerontology, 2011 - Springer
Wound healing becomes impaired in several diseases and during ageing. A commonly
used model for the study of wound healing is a scratched monolayer of cells in vitro, which is …

Phytochemicals in the treatment of Alzheimer's disease: a systematic review

G D'Onofrio, D Sancarlo, Q Ruan, Z Yu… - Current Drug …, 2017 - ingentaconnect.com
Background: Alzheimer's disease (AD) is the most widespread age-related
neurodegenerative disease. Recently, a growing body of evidence suggested the …

Molecular bases of caloric restriction regulation of neuronal synaptic plasticity

Á Fontán-Lozano, G López-Lluch… - Molecular …, 2008 - Springer
Aging is associated with the decline of cognitive properties. This situation is magnified when
neurodegenerative processes associated with aging appear in human patients. Neuronal …

Effect of the intake of resveratrol, resveratrol phosphate, and catechin-rich grape seed extract on markers of oxidative stress and gene expression in adult obese …

D De Groote, K Van Belleghem, J Devière… - Annals of Nutrition and …, 2012 - karger.com
Background: The preventive effect of resveratrol (RES) on the development of human
diseases has been verified by numerous epidemiological studies. Resveratrol triphosphate …

Natural Xanthones from Garcinia mangostana with Multifunctional Activities for the Therapy of Alzheimer's Disease

S Wang, Q Li, M Jing, E Alba, X Yang, R Sabaté… - Neurochemical …, 2016 - Springer
Natural xanthones have diversity pharmacological activities. Here, a series of xanthones
isolated from the pericarps of Garcinia mangostana Linn, named α-Mangostin, 8 …

Lycopene suppresses palmitic acid-induced brain oxidative stress, hyperactivity of some neuro-signalling enzymes, and inflammation in female Wistar rat

RN Ugbaja, AS James, EI Ugwor, AJ Akamo… - Scientific reports, 2021 - nature.com
Neuroinflammation can be triggered by certain high caloric nutrients such as palmitic acid
(PA). The effect of lycopene against PA-induced neuroinflammation in female rats has not …

The heme oxygenase/biliverdin reductase pathway in drug research and development

C Mancuso, E Barone - Current drug metabolism, 2009 - ingentaconnect.com
The heme oxygenase/biliverdin reductase (HO/BVR) axis catalyzes the degradation of
heme, but this system and its byproducts, carbon monoxide (CO) and bilirubin, have also …

In Vivo Monitoring of Sevoflurane-induced Adverse Effects in Neonatal Nonhuman Primates Using Small-animal Positron Emission Tomography

X Zhang, S Liu, GD Newport, MG Paule, R Callicott… - …, 2016 - pubs.asahq.org
Background Animals exposed to sevoflurane during development sustain neuronal cell
death in their developing brains. In vivo micro-positron emission tomography …

Advances in integrative nanomedicine for improving infectious disease treatment in public health

IR Bell, GE Schwartz, NN Boyer, M Koithan… - European journal of …, 2013 - Elsevier
INTRODUCTION: Infectious diseases present public health challenges worldwide. An
emerging integrative approach to treating infectious diseases is using nanoparticle (NP) …

Sulforaphane Upregulates the Heat Shock Protein Co‐Chaperone CHIP and Clears Amyloid‐β and Tau in a Mouse Model of Alzheimer's Disease

S Lee, BR Choi, J Kim, FM LaFerla… - Molecular nutrition & …, 2018 - Wiley Online Library
Scope Sulforaphane is an herbal isothiocyanate enriched in cruciferous vegetables. Here,
the authors investigate whether sulforaphane modulates the production of amyloid‐β (Aβ) …