Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Cryptococcal meningitis is a leading cause of morbidity and mortality globally, especially in
people with advanced HIV disease. Cryptococcal meningitis is responsible for nearly 20% of …

Cryptococcal meningoencephalitis was first described over a century ago. This fungal
infection is preventable and treatable yet continues to be associated with excessive …

Appropriate diagnosis of invasive fungal infections (IFIs) is critical due to the high rates of
morbidity and mortality, as well as the substantial economic burden, associated with the …

Cryptococcal antigen (CrAg) is detectable in blood prior to the onset of symptomatic
cryptococcal meningitis (CM), a leading cause of death among people with advanced …

Introduction Survival among people with HIV-associated cryptococcal meningitis (CM)
remains low, particularly among women, despite the currently optimal use of antifungal …

Background Early diagnosis of HIV infection and early initiation of ART before
immunosuppression is the most important strategy to reduce the incidence of CM and CM …

Background Fungal infections are common in HIV-infected individuals and significantly
contribute to mortality. However, a substantial number of cases are undiagnosed before …

Cryptococcosis is a neglected tropical disease and the main cause of fungal-related deaths
in HIV-positive persons in Africa. It is an AIDS-defining illness that has almost surpassed …

Immune reconstitution inflammatory syndrome (IRIS) presents as an exaggerated immune
reaction that occurs during dysregulated immune restoration in immunocompromised …