[HTML][HTML] Non-coding RNAs participate in the ischemia-reperfusion injury

S Ghafouri-Fard, H Shoorei, M Taheri - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Ischemia, being defined as blood supply deficiency is involved in the pathogenesis of a
number of life-threatening conditions such as myocardial infarction and cerebral stroke …

Oxidative stress, inflammation, and autophagy: potential targets of mesenchymal stem cells-based therapies in ischemic stroke

J He, J Liu, Y Huang, X Tang, H Xiao… - Frontiers in Neuroscience, 2021 - frontiersin.org
Ischemic stroke is a leading cause of death worldwide; currently available treatment
approaches for ischemic stroke are to restore blood flow, which reduce disability but are time …

Long non-coding RNAs as promising therapeutic approach in ischemic stroke: a comprehensive review

M Wolska, J Jarosz-Popek, E Junger, Z Wicik… - Molecular …, 2021 - Springer
In recent years, ischemic stroke (IS) has been one of the major causes of disability and
mortality worldwide. The general mechanism of IS is based on reduced blood supply to …

Combination of paeoniflorin and calycosin-7-glucoside alleviates ischaemic stroke injury via the PI3K/AKT signalling pathway

PC Wang, SX Wang, XL Yan, YY He… - Pharmaceutical …, 2022 - Taylor & Francis
Context Paeoniflorin (PF) and calycosin-7-glucoside (CG, Paeonia lactiflora Pall. extract)
have demonstrated protective effects in ischaemic stroke. Objective To investigate the …

[HTML][HTML] Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of …

Y Huang, F Tan, Y Zhuo, J Liu, J He, D Duan… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Microglial cells are the first line immune cells that initiate inflammatory responses following
cerebral ischemia/reperfusion (I/R) injury. Microglial cells are also associated with a novel …

Dexmedetomidine Inhibits Gasdermin D-Induced Pyroptosis via the PI3K/AKT/GSK3β Pathway to Attenuate Neuroinflammation in Early Brain Injury After …

B Wei, W Liu, L Jin, S Guo, H Fan, F Jin… - Frontiers in Cellular …, 2022 - frontiersin.org
Subarachnoid hemorrhage (SAH) is one kind of life-threatening stroke, which leads to
severe brain damage. Pyroptosis plays a critical role in early brain injury (EBI) after SAH …

Gli2-induced lncRNA Peg13 alleviates cerebral ischemia-reperfusion injury by suppressing Yy1 transcription in a PRC2 complex-dependent manner

Y Li, C Liu, H Fan, Y Du, R Zhang, S Zhan… - Metabolic Brain …, 2023 - Springer
Endothelial cell dysfunction plays an important role in cerebral ischemia-reperfusion (I/R)
injury. LncRNA Peg13 is reported to be down-regulated in brain microvascular endothelial …

Unveiling the therapeutic potential of non-coding RNAs in stroke-induced tissue regeneration

A Waseem, AQ Khan, MA Khan, R Khan, S Uddin… - Stem Cells, 2023 - academic.oup.com
Stroke is a major contributor to mortality and impairment on a global scale, with few effective
treatments available. Aberrant expression of various non-coding RNAs (ncRNAs) has been …

OM‐MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF‐PI3K/Akt/mTOR Signaling Pathway

J He, J Liu, Y Huang, X Tang, H Xiao… - Oxidative Medicine …, 2021 - Wiley Online Library
The mechanism of Golgi apparatus (GA) stress responses mediated by GOLPH3 has been
widely studied in ischemic stroke, and the neuroprotection effect of olfactory mucosa …

Mesenchymal stem cell therapy for ischemic stroke: Novel insight into the crosstalk with immune cells

N Tan, W Xin, M Huang, Y Mao - Frontiers in Neurology, 2022 - frontiersin.org
Stroke, a cerebrovascular accident, is prevalent and the second highest cause of death
globally across patient populations; it is as a significant cause of morbidity and mortality …