Tumor microenvironment in prostate cancer: toward identification of novel molecular biomarkers for diagnosis, prognosis, and therapy development
Prostate cancer (PCa) is by far the most commonly diagnosed cancer in men worldwide.
Despite sensitivity to androgen deprivation, patients with advanced disease eventually …
Despite sensitivity to androgen deprivation, patients with advanced disease eventually …
Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases
AL Hardaway, MK Herroon, E Rajagurubandara… - Cancer and Metastasis …, 2014 - Springer
Adipocytes are important but underappreciated components of bone marrow
microenvironment, and their numbers greatly increase with age, obesity, and associated …
microenvironment, and their numbers greatly increase with age, obesity, and associated …
Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and …
Background Tumour-derived extracellular vesicles (EVs) play a role in tumour progression;
however, the spectrum of molecular mechanisms regulating EV secretion and cargo …
however, the spectrum of molecular mechanisms regulating EV secretion and cargo …
A pH‐sensitive, biobased calcium carbonate aragonite nanocrystal as a novel anticancer delivery system
A Shafiu Kamba, M Ismail… - BioMed research …, 2013 - Wiley Online Library
The synthesised biobased calcium carbonate nanocrystals had demonstrated to be an
effective carrier for delivery of anticancer drug doxorubicin (DOX). The use of these …
effective carrier for delivery of anticancer drug doxorubicin (DOX). The use of these …
Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases: a network meta‐analysis
T Jakob, YM Tesfamariam, S Macherey… - Cochrane Database …, 2020 - cochranelibrary.com
Background Different bone‐modifying agents like bisphosphonates and receptor activator of
nuclear factor‐kappa B ligand (RANKL)‐inhibitors are used as supportive treatment in men …
nuclear factor‐kappa B ligand (RANKL)‐inhibitors are used as supportive treatment in men …
Bone marrow sinusoidal endothelium: damage and potential regeneration following cancer radiotherapy or chemotherapy
It is very well known that bone marrow (BM) microvasculature may possess a crucial role in
the maintenance of homeostasis of BM due to mutual interactions between BM …
the maintenance of homeostasis of BM due to mutual interactions between BM …
Prostate cancer with bone metastasis in Beijing: an observational study of prevalence, hospital visits and treatment costs using data from an administrative claims …
L Zhuo, Y Cheng, Y Pan, J Zong, W Sun, L Xu… - BMJ open, 2019 - bmjopen.bmj.com
Objectives To estimate the prevalence of prostate cancer with bone metastasis in Beijing,
and to estimate hospital visits and direct treatment costs among male urban employees with …
and to estimate hospital visits and direct treatment costs among male urban employees with …
Advanced prostate cancer: reinforcing the strings between inflammation and the metastatic behavior
G Gueron, A De Siervi, E Vazquez - Prostate Cancer and Prostatic …, 2012 - nature.com
It is currently estimated that inflammatory responses are linked to 15–20% of all deaths from
cancer worldwide. Although many studies point to an important role of inflammation in …
cancer worldwide. Although many studies point to an important role of inflammation in …
Targeting integrin α6 stimulates curative-type bone metastasis lesions in a xenograft model
TH Landowski, J Gard, E Pond, GD Pond… - Molecular cancer …, 2014 - AACR
Laminin-binding integrin receptors are key mediators of epithelial cell migration and tumor
metastasis. Recent studies have demonstrated a role for the α6 integrin (ITGA6/CD49f) in …
metastasis. Recent studies have demonstrated a role for the α6 integrin (ITGA6/CD49f) in …
11C-choline PET/CT identifies osteoblastic and osteolytic lesions in patients with metastatic prostate cancer
F Ceci, P Castellucci, T Graziani… - Clinical nuclear …, 2015 - journals.lww.com
Aim The aim of this study was to compare 11 C-choline PET/CT, prostate-specific antigen
(PSA), PSA kinetics, and 11 C-choline uptake in recurrent metastatic prostate cancer …
(PSA), PSA kinetics, and 11 C-choline uptake in recurrent metastatic prostate cancer …