A review: Mechanism of action of antiviral drugs

S Kausar, F Said Khan… - International journal …, 2021 - journals.sagepub.com
Antiviral drugs are a class of medicines particularly used for the treatment of viral infections.
Drugs that combat viral infections are called antiviral drugs. Viruses are among the major …

Seeking heterocyclic scaffolds as antivirals against dengue virus

S De, B Aamna, R Sahu, S Parida, SK Behera… - European Journal of …, 2022 - Elsevier
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …

Current Development of Thiazole-Containing Compounds as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus

H Liu, T Xu, Z Xue, M Huang, T Wang… - ACS Infectious …, 2024 - ACS Publications
The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …

Synthesis and characterization of Co (II), Ni (II), Cu (II) and Zn (II) chelates: DFT calculations, molecular docking and biological applications

AA Helaly, AA El-Bindary, SA Elsayed - Journal of Molecular Liquids, 2023 - Elsevier
An azo dye ligand,(Z)-2-(benzo [d] thiazol-2-yl)-2-(2-p-tolylhydrazono) acetonitrile (HL) and
its Co (II)(1), Cu (II)(2), Ni (II)(3) and Zn (II)(4) chelates were synthesized and considered …

Adsorption study of N (-benzo [d] thiazol-2-yl)-1-(thiophene-2-yl) methanimine at mild steel/aqueous H2SO4 interface

AK Singh, M Singh, S Thakur, B Pani, S Kaya… - Surfaces and …, 2022 - Elsevier
This study reports microwave (MW) assisted synthesis of N (-benzo [d] thiazol-2-yl)-1-
(thiophene-2-yl) methanimine (BTTM) in reasonably good yield and purity. The synthesized …

[HTML][HTML] Thiazolidin-4-ones as potential antimicrobial agents: Experimental and in silico evaluation

C Tratrat, A Petrou, A Geronikaki, M Ivanov, M Kostić… - Molecules, 2022 - mdpi.com
Herein, we report computational and experimental evaluations of the antimicrobial activity of
twenty one 2, 3-diaryl-thiazolidin-4-ones. All synthesized compounds exhibited an …

Exploring biological efficacy of novel benzothiazole linked 2, 5-disubstituted-1, 3, 4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization …

M Duhan, P Kumar, J Sindhu, R Singh, M Devi… - Computers in Biology …, 2021 - Elsevier
In an effort to explore a class of novel antidiabetic agents, we have made an effort to
synergize the α-amylase inhibitory potential of 1, 3-benzothiazole and 1, 3, 4-oxadiazole …

Novel benzothiazole hybrids targeting EGFR: Design, synthesis, biological evaluation and molecular docking studies

EA Abd El-Meguid, GO Moustafa, HM Awad… - Journal of Molecular …, 2021 - Elsevier
Novel benzo [d] thiazole-based analogues were synthesized with the aim of screening their
in vitro anticancer activity. All the new derivatives 4–21 were evaluated against human …

[HTML][HTML] Modern approaches to the synthesis and transformations of practically valuable benzothiazole derivatives

LV Zhilitskaya, BA Shainyan, NO Yarosh - Molecules, 2021 - mdpi.com
The review is devoted to modern trends in the chemistry of 2-amino and 2-mercapto
substituted benzothiazoles covering the literature since 2015. The reviewed heterocycles …

Design, synthesis, docking study, and anticancer evaluation of novel bis-thiazole derivatives linked to benzofuran or benzothiazole moieties as PI3k inhibitors and …

IT Radwan, AHM Elwahy, AF Darweesh… - Journal of Molecular …, 2022 - Elsevier
A molecular hybridization approach was used to construct and develop a variety of new bis-
thiazoles coupled to benzofuran or benzothiazole moieties as anticancer drugs. The target …