[HTML][HTML] Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine

C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …

Immune determinants of chronic sequelae after respiratory viral infection

H Narasimhan, Y Wu, NP Goplen, J Sun - Science Immunology, 2022 - science.org
The acute effects of various respiratory viral infections have been well studied, with
extensive characterization of the clinical presentation as well as viral pathogenesis and host …

Clinical, radiological and pathological findings in patients with persistent lung disease following SARS-CoV-2 infection

C Ravaglia, C Doglioni, M Chilosi… - European …, 2022 - Eur Respiratory Soc
Some patients experience pulmonary sequelae after SARS-CoV-2 infection, ranging from
self-limited abnormalities to major lung diseases. Morphological analysis of lung tissue may …

[HTML][HTML] Nasally delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron

Z Chong, CE Karl, PJ Halfmann, Y Kawaoka… - Cell reports, 2022 - cell.com
Although vaccines and monoclonal antibody countermeasures have reduced the morbidity
and mortality associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Prevalence and mechanisms of mucus accumulation in COVID-19 lung disease

T Kato, T Asakura, CE Edwards, H Dang… - American journal of …, 2022 - atsjournals.org
Rationale: The incidence and sites of mucus accumulation and molecular regulation of
mucin gene expression in coronavirus (COVID-19) lung disease have not been reported …

A nasal cell atlas reveals heterogeneity of tuft cells and their role in directing olfactory stem cell proliferation

S Ualiyeva, E Lemire, C Wong, A Perniss… - Science …, 2024 - science.org
The olfactory neuroepithelium serves as a sensory organ for odors and forms part of the
nasal mucosal barrier. Olfactory sensory neurons are surrounded and supported by …

[HTML][HTML] IL-33 biology in cancer: An update and future perspectives

WJ Yeoh, VP Vu, P Krebs - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that is constitutively
expressed in the nucleus of epithelial, endothelial and fibroblast-like cells. Upon cell stress …

[HTML][HTML] COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes

C Wang, MS Khatun, Z Zhang, MJ Allen… - Communications …, 2023 - nature.com
SARS-CoV-2 infection can cause persistent respiratory sequelae. However, the underlying
mechanisms remain unclear. Here we report that sub-lethally infected K18-human ACE2 …

[HTML][HTML] ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

AI Weiner, G Zhao, HM Zayas, NP Holcomb… - Cell reports, 2022 - cell.com
The lung exhibits a robust, multifaceted regenerative response to severe injuries such as
influenza infection, during which quiescent lung-resident epithelial progenitors participate in …

[HTML][HTML] A deep view of the biological property of interleukin-33 and its dysfunction in the gut

Y Wang, C He, S Xin, X Liu, S Zhang, B Qiao… - International Journal of …, 2023 - mdpi.com
Intestinal diseases have always posed a serious threat to human health, with inflammatory
bowel disease (IBD) being one of them. IBD is an autoimmune disease characterized by …