[HTML][HTML] Natural small molecules in breast cancer treatment: understandings from a therapeutic viewpoint

MR Islam, F Islam, MH Nafady, M Akter, S Mitra, R Das… - Molecules, 2022 - mdpi.com
Breast cancer (BrCa) is the most common malignancy in women and the second most
significant cause of death from cancer. BrCa is one of the most challenging malignancies to …

[HTML][HTML] The biological and molecular action of ozone and its derivatives: state-of-the-art, enhanced scenarios, and quality insights

V Travagli, EL Iorio - International Journal of Molecular Sciences, 2023 - mdpi.com
The ultimate objective of this review is to encourage a multi-disciplinary and integrated
methodological approach that, starting from the recognition of some current uncertainties …

Deciphering the pharmacological mechanisms of Rostellularia procumbens (L) Nees. Extract alleviates adriamycin‐induced nephropathy in vivo and in vitro

Z Ai, M Wang, Y Zhou, D Yuan, Q Jian, S Wu, B Liu… - Phytomedicine, 2023 - Elsevier
Abstract Background Rostellularia procumbens (L) Nees. is an effective traditional Chinese
herbal medicine for the treatment of patients with chronic glomerulonephritis (CGN) in the …

Melatonin and cisplatin co-treatment against cancer: a mechanistic review of their synergistic effects and melatonin's protective actions

M Rafiyan, A Davoodvandi, RJ Reiter… - … -Research and Practice, 2023 - Elsevier
Combination chemotherapy appears to be a preferable option for some cancer patients,
especially when the medications target multiple pathways of oncogenesis; individuals …

[HTML][HTML] The protective role of ozone therapy in kidney disease: a review

LF Delgadillo-Valero, EY Hernández-Cruz… - Life, 2023 - mdpi.com
Ozone (O3) is a reactive oxygen species (ROS) that can interact with cellular components
and cause oxidative stress. Following said logic, if O3 induces such a stressful milieu, how …

[HTML][HTML] Educational review: the impact of perinatal oxidative stress on the developing kidney

MJ DeFreitas, CP Katsoufis, M Benny, K Young… - Frontiers in …, 2022 - frontiersin.org
Oxidative stress occurs when there is an imbalance between reactive oxygen
species/reactive nitrogen species and antioxidant systems. The interplay between these …

[HTML][HTML] Acrylamide-targeting renal miR−21a−5p/Fibrotic and miR122-5p/ inflammatory signaling pathways and the role of a green approach for nano-zinc detected via in silico …

LS Alqahtani, ME Alosaimi… - Frontiers in …, 2024 - frontiersin.org
Introduction: Any disruption in renal function can have cascading effects on overall health.
Understanding how a heat-born toxicant like acrylamide (ACR) affects kidney tissue is vital …

Identification and validation of the surface proteins FIBG, PDGF-β, and TGF-β on serum extracellular vesicles for non-invasive detection of colorectal cancer …

Z Huang, C Deng, C Ma, G He, J Tao… - … Journal of Surgery, 2024 - journals.lww.com
Objectives: The absence of non-invasive biomarkers for the early diagnosis of colorectal
cancer (CRC) has contributed to poor prognosis. Extracellular vesicles (EVs) have emerged …

Fenpropathrin provoked kidney damage via controlling the NLRP3/Caspase-1/GSDMD–mediated pyroptosis: The palliative role of curcumin-loaded chitosan …

YM Abd-Elhakim, AAR Mohamed, AE Noreldin… - Toxicology and Applied …, 2024 - Elsevier
This study assessed the ability of formulated curcumin-loaded chitosan nanoparticles (CU-
CS-NPs) to reduce the kidney damage resulting from fenpropathrin (FPN) in rats compared …

[HTML][HTML] SIRT1 activation ameliorates rhesus monkey liver fibrosis by inhibiting the TGF-β/smad signaling pathway

Y Xia, Q Luo, Q Gao, C Huang, P Chen, Y Zou… - Chemico-Biological …, 2024 - Elsevier
TGF-β/Smad signaling pathway plays an important role in the pathogenesis and progression
of liver fibrosis. Silent information regulator 1 (SIRT1) is a nicotinamide adenine dinucleotide …