Purpose Osteoarthritis (OA) is a joint disease that is clinically diagnosed using components
of history, physical exam, and characteristic radiographic findings, such as joint space …

Although great progress has been made in the use of Omics approaches to OA, in both
animal models and patient samples, much work remains to be done. In addition to filling …

Objective Osteoarthritis is a heterogeneous disease. The objective was to compare
differences in underlying cellular mechanisms and endogenous repair pathways between …

With the rise in longevity within the population, medicine continues to encounter fresh
hurdles necessitating prompt actions, among which are those associated with hip joint …

Objective Obesity is a leading risk factor for both the incidence and progression of
osteoarthritis (OA). Omic technologies, including transcriptomics and metabolomics are …

Objective: The Intensive Diet and Exercise for Arthritis (IDEA) trial was conducted to evaluate
the effects of diet and exercise on osteoarthritis (OA), the most prevalent form of arthritis …

Noninvasive compression-induced anterior cruciate ligament rupture (ACL-R) is an easy
and reproducible model for studying post-traumatic osteoarthritis (PTOA) in mice. However …

Osteoarthritis (OA) afflicts millions of people each year. The onset of OA has been
associated with many factors including increased bone-cartilage fluid transport, yet a cure …

Metabolomic studies have improved the understanding of a broad range of biological
tissues, fluids, and systems. Typically, metabolomic analyses employ a workflow that starts …

Objective Post-traumatic osteoarthritis (PTOA) is a common long-term outcome following
ACL injury. However, early changes to bone and synovial fluid after ACL injury are not …